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Antiphospholipid Syndrome

  • Abhishek PurohitEmail author
  • Mayank Kumar
Chapter

Abstract

Antiphospholipid syndrome (APS) is a prothrombotic condition with immune pathogenesis that is characterized by thrombosis in the venous or arterial vasculature and/or pregnancy morbidity, which occurs in the presence of persistent laboratory evidence of antiphospholipid antibodies (aPLs). aPLs are autoantibodies that target phospholipid-bound proteins, especially β2-glycoprotein I (β2-GPI). The presence of these antibodies is the defining feature of this syndrome; however, the mechanism by which aPLs cause a hypercoagulable state is not fully understood [1].

Keywords

APS Lupus thrombosis 

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Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  1. 1.Department of PathologyAll India Institute of Medical SciencesJodhpurIndia

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