Current Management of Ocular Surface Squamous Neoplasia (OSSN)

  • S. Madison Duff
  • Niloofar Piri
  • Hossein AsghariEmail author
Part of the Current Practices in Ophthalmology book series (CUPROP)


Ocular surface squamous neoplasia (OSSN) is a superficial conjunctival and cornea tumor but 3–9% can have intraocular invasion and approximately 1–6% can have orbital invasion. Primary treatment remains surgical but use of topical chemotherapy has greatly improved the outcome for extensive lesions and for recurrent tumors. Radiation and enucleation or exenteration are reserved for extensive lesions.


Squamous cell carcinoma Carcinoma in situ (CIN) Mitomycin Interferon 5-Fluorouracil 


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Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • S. Madison Duff
    • 1
  • Niloofar Piri
    • 1
  • Hossein Asghari
    • 1
    Email author
  1. 1.University of Louisville OphthalmologyLouisvilleUSA

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