Molecular Imaging and Targeted Therapy of Gastrointestinal Cancer

  • Menghui Yuan
  • Hua Pang


Gastrointestinal (GI) cancer constitutes an important health issue worldwide and is responsible for most cancer-related fatalities in both genders. GI malignancies such as colorectal, gastric, and esophageal tumors are on the rise. Multiple treatment approaches are currently used for GI cancer but with limited effect.


  1. 1.
    Alan PV, Christos P, Junji F et al (2010) The incidence and epidemiology of hepatocellular carcinoma: a global and regional perspective. Oncologist 15(Suppl 4):5–13Google Scholar
  2. 2.
    Federico I, Kouros O, Nancy LC et al (2012) A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303. Clin Cancer Res 18:577–584CrossRefGoogle Scholar
  3. 3.
    Castilla-Lièvre M-A, Franco D, Gervais P et al (2016) Diagnostic value of combining 11C-choline and 18F-FDG PET/CT in hepatocellular carcinoma. Eur J Nucl Med Mol Imaging 43:852–859CrossRefGoogle Scholar
  4. 4.
    Valle JW, Borbath I, Khan SA et al (2016) Biliary cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 27(suppl_5):v28–v37Google Scholar
  5. 5.
    Priyanka J, Bijan B (2015) PET/CT for pancreatic malignancy: potential and pitfalls. J Nucl Med Technol 43:92–97CrossRefGoogle Scholar
  6. 6.
    Woohyun J, Jin-Young J, Mee Joo K (2016) The clinical usefulness of 18F-fluorodeoxyglucose positron emission tomography–computed tomography (PET–CT) in follow-up of curatively resected pancreatic cancer patients. HPB 18:57–64CrossRefGoogle Scholar
  7. 7.
    Khan SA, Davidson BR, Goldin RD et al (2012) Guidelines for the diagnosis and treatment of cholangiocarcinoma: an update. Gut 61(12):1657–1669Google Scholar
  8. 8.
    Brito AF, Abrantes AM, Encarnacao JC et al (2015) Cholangiocarcinoma: from molecular biology to treatment. Med Oncol 32(11):245CrossRefGoogle Scholar

Copyright information

© Springer Nature Singapore Pte Ltd. and Shanghai Jiao Tong University Press 2019

Authors and Affiliations

  • Menghui Yuan
    • 1
  • Hua Pang
    • 2
  1. 1.Tangdu Hospital of the Forth Military and Medical UniversityXi’anP. R. China
  2. 2.The First Affiliated Hospital of Chongqing Medical UniversityChongqingP. R. China

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