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Novel Molecular Probes

  • Min YangEmail author
  • Yuping Xu
  • Xinyu Wang
  • Yu Liu
  • Yanting Wang
  • Huimin Zhao
  • Jie Sheng
  • Yaoqi Li
Chapter

Abstract

Molecular imaging is important for early disease diagnosis, personalized therapy guidance, and new drug development. Nuclear scintigraphy using SPECT or PET is the widely used example in the clinic. To achieve functional visualization, specific probes are indispensable. For nuclear probes, radionuclides and targeting ligands (small compounds, peptide, affibody, etc.) are the main contents (Fig. 20.1). Some popular radioisotopes are listed in Table 20.1. In this chapter, we focused on 18F-, 11C-, 68Ga-, 89Zr-, 64Cu-, 90Y-, and 177Lu-labeled probes.

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Copyright information

© Springer Nature Singapore Pte Ltd. and Shanghai Jiao Tong University Press 2019

Authors and Affiliations

  • Min Yang
    • 1
    Email author
  • Yuping Xu
    • 1
  • Xinyu Wang
    • 1
  • Yu Liu
    • 1
  • Yanting Wang
    • 1
  • Huimin Zhao
    • 1
  • Jie Sheng
    • 1
  • Yaoqi Li
    • 1
  1. 1.Key Laboratory of Nuclear Medicine, Ministry of Health, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear MedicineWuxiP.R. China

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