Alcoholic Liver Disease and Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis

  • Etsuko HashimotoEmail author
  • Masaki Iwai
  • Arief A. Suriawinata


Alcoholic liver disease (ALD) has been reported worldwide with a prevalence of 0–20% and remains one of the major causes of liver disease. The spectrum of ALD includes fatty liver, alcoholic hepatitis, alcoholic fibrosis, and cirrhosis. Hepatocellular carcinoma may also develop, especially in patients with cirrhosis. Histologically, ALD shows simple steatosis and steatohepatitis and eventually progresses to cirrhosis. These clinical and histological features overlap.


Alcoholic liver disease Nonalcoholic fatty liver disease Nonalcoholic fatty liver Nonalcoholic steatohepatitis Fatty liver Cirrhosis Hepatocellular carcinoma 



Prof. Paul Y. Kwo is acknowledged for his contribution in editing this chapter.


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Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Etsuko Hashimoto
    • 1
    Email author
  • Masaki Iwai
    • 2
  • Arief A. Suriawinata
    • 3
  1. 1.TokyoJapan
  2. 2.KyotoJapan
  3. 3.New HampshireUSA

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