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Metastatic Liver Tumors

  • Louis J. Vaickus
  • Arief A. SuriawinataEmail author
  • Masaki Iwai
Chapter

Abstract

Metastatic tumors are the most common type of malignancy in the liver, far exceeding primary tumors of the liver. The distinction between a primary tumor and a metastatic tumor in the liver has both therapeutic and prognostic significance. Knowledge of the primary tumor site and its morphology, if available, is important in evaluating and comparing it to its metastasis. Among tumor types, adenocarcinoma, neuroendocrine tumor, and lymphoma are the most common. Common primary sites include the colon (adenocarcinoma), pancreas (adenocarcinoma and pancreatic neuroendocrine tumor), stomach and small intestine (adenocarcinoma, neuroendocrine and gastrointestinal stromal tumor), lung (adenocarcinoma, small-cell and large-cell neuroendocrine carcinoma, and squamous cell carcinoma), breast, skin (melanoma), and kidney (renal cell carcinoma).

Keywords

Metastasis Liver Tumor Metastatic tumor 

Abbreviations

AFP

Alpha-fetoprotein

ALT

Alanine aminotransferase

AST

Aspartate aminotransferase

CK

Cytokeratin

CT

Computed tomography

GGT

Gamma-glutamyl transferase

LDH

Lactate dehydrogenase

TBIL

Total bilirubin

Notes

Acknowledgement

Prof. Alex Y. Chang was a coauthor of the first edition of this chapter.

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Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Louis J. Vaickus
    • 1
  • Arief A. Suriawinata
    • 1
    Email author
  • Masaki Iwai
    • 2
  1. 1.New HampshireUSA
  2. 2.Gastroenterology, Hepatology and Internal MedicineIwai ClinicKyotoJapan

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