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Liver Disorders in Systemic Diseases

  • Masaki Iwai
  • Kenichi Miyoshi
  • Masahiko Koda
  • Wilson M. S. TsuiEmail author
Chapter

Abstract

Liver disease may occur in association with various systemic diseases. These primary diseases are predominantly extrahepatic, but associated hepatic dysfunction may develop and often is of clinical significance and diagnostic importance. In some cases, liver disease simply represents a manifestation of the systemic disease process involving the liver, as in disseminated malignancy, systemic infection, and some metabolic diseases. Rarely, it may constitute a relatively unique manifestation of a systemic disease, as in primary sclerosing cholangitis associated with ulcerative colitis.

Abbreviations

AIDS

Acquired immunodeficiency syndrome

ANC

Absolute neutrophil count

C-MOPP-ABVD

Combination chemotherapy-Mustargen, oncovin, procarbazine, prednisone-Adriamycin, bleomycin, vinblastine, dacarbazine

CREST

Calcinosis cutis, Raynaud’s phenomenon, esophageal dysfunction, sclerodactyly, and telangiectasia

DIC

Disseminated intravascular coagulopathy

EMH

Extramedullary hemopoiesis

HELLP

Hemolysis, elevated liver tests, and low platelets

IBD

Inflammatory bowel disease

MALT

Mucosa-associated lymphoid tissue

MDR3

Multidrug resistance protein 3

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Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Masaki Iwai
    • 1
  • Kenichi Miyoshi
    • 2
  • Masahiko Koda
    • 2
  • Wilson M. S. Tsui
    • 3
    Email author
  1. 1.KyotoJapan
  2. 2.TottoriJapan
  3. 3.Hong KongChina

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