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Granulomatous Liver Diseases

  • Masako Mishima
  • Masahiko Koda
  • Wilson M. S. Tsui
Chapter

Abstract

Hepatic granulomas develop through the interactions of T lymphocytes and macrophages. Granulomas are relatively common in liver samples, identified in 2–10% of cases. Granuloma formation is mainly due to infections, sarcoidosis, drug reactions, and primary biliary cholangitis. This article concisely reviews the classification, etiology, pathophysiology, clinical presentation, diagnosis, and treatment options of granulomatous liver diseases.

Keywords

Granuloma Kupffer cell Lipogranuloma An epithelioid granuloma An inflammatory granuloma Sarcoidosis Primary biliary cholangitis Hepatic tuberculosis Bacillus Calmette-Guerin Syphilis Schistosomiasis Drug Lymphoma 

Abbreviations

BCG

Bacillus Calmette-Guerin

HIV

Human immunodeficiency virus

PBC

Primary biliary cholangitis

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Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Masako Mishima
    • 1
  • Masahiko Koda
    • 2
  • Wilson M. S. Tsui
    • 3
  1. 1.KyotoJapan
  2. 2.TottoriJapan
  3. 3.Hong KongChina

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