Advertisement

Experimental Animal Studies

  • Jayanta Kumar Patra
  • Swagat Kumar Das
  • Gitishree Das
  • Hrudayanath Thatoi
Chapter
Part of the Learning Materials in Biosciences book series (LMB)

Abstract

Blood sample from experimental animals are frequently required for study of effect of drugs on biochemical parameters and for the study of pharmacokinetics of drugs in the experimental animals. One important aspect of the blood sample collection is that the experimental animals should feel least stress and pain as the blood collection under stressful condition may affect the outcome of the experiment. The blood sample is generally collected from venous, arterial blood vessels or heart chambers. However, several factors need to be considered for collection of blood from experimental animals. Such as:

References

  1. Badyal D (2008) Practical manual of pharmacology. Jaypee Brothers Medical Publishers, New DelhiCrossRefGoogle Scholar
  2. BM Swamy V, Jayaveera KN, Reddy V (2014) Experimental pharmacology and toxicology. S. Chand & Company, New DelhiGoogle Scholar
  3. Goyal RK (2017) Practical in pharmacology. B. S. Shah Prakashan, AhmedabadGoogle Scholar
  4. Kale SR, Kale RR (2017) Practical pharmacology and toxicology. Nirali Prakashan, MumbaiGoogle Scholar
  5. Katzung BG, Masters SB, Trevor AJ (2012) Basic & clinical pharmacology. McGraw-Hill, New YorkGoogle Scholar
  6. Medhi B (2017) Practical manual of experimental and clinical pharmacology. Jaypee Brothers Medical Publishers, New DelhiGoogle Scholar
  7. Ritter JM, Lewis LD, Mant TGK, Ferro A (2008) A text book of clinical pharmacology and therapeutics. Hodder Arnold, LondonCrossRefGoogle Scholar
  8. Salmon DM (2014) Practical pharmacology for the pharmaceutical sciences. Wiley, ChichesterGoogle Scholar
  9. Sierra LM, Gaivao I (eds) (2014) Genotoxicity and DNA repair: a practical approach. Springer protocols. Humana Press, LondonGoogle Scholar
  10. Singhal KC (1997) Pharmacology laboratory manual. CBS Publishers & Distributor, New DelhiGoogle Scholar
  11. Thatoi HN, Dash S, Das SK (2017) Practical biotechnology, principle and protocols. I.K. International, New DelhiGoogle Scholar
  12. Tripathi KD (2013) Essentials of medical pharmacology. Jaypee Brothers Medical Publishers, New DelhiGoogle Scholar
  13. Turner RA, Hebborn P (eds) (1971) Screening methods in pharmacology. Academic, New YorkGoogle Scholar
  14. Vogel HG (ed) (2002) Drug discovery and evaluation pharmacological assays. Springer, BerlinGoogle Scholar
  15. Woolley A (2008) A guide to practical toxicology. Informa Healthcare USA, New YorkCrossRefGoogle Scholar

Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Jayanta Kumar Patra
    • 1
  • Swagat Kumar Das
    • 2
  • Gitishree Das
    • 3
  • Hrudayanath Thatoi
    • 4
  1. 1.Research Institute of Biotechnology & Medical Converged ScienceDongguk UniversityGoyang-siSouth Korea
  2. 2.Department of BiotechnologyCollege of Engineering and Technology, Biju Patnaik University of TechnologyOdishaIndia
  3. 3.Dongguk UniversityGoyang-siSouth Korea
  4. 4.Department of BiotechnologyNorth Orissa UniversityOdishaIndia

Personalised recommendations