Germline Signaling Pathways Required for the Regulation of Toxicity of Environmental Toxicants or Stresses
In this chapter, we focused on the introduction of germline signaling pathways involved in the regulation of toxicity of environmental toxicants or stresses in nematodes. We first discussed the crucial role of germline for the toxicity induction in nematodes exposed to certain environmental toxicants or stresses. Moreover, the important functions of germline ERK and insulin signaling pathways and their communication with somatic signals in regulating the toxicity of environmental toxicants or stresses were further introduced and discussed.
KeywordsGermline signaling pathway Environmental exposure Caenorhabditis elegans
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