Recent Advances in Molecular Diagnostic Approaches for Cancer
Globally cancer is considered as a disease of high morbidity and mortality, which includes a group of diseases having uncontrolled cell growth and proliferation. Most cancers are curable if detected at an early stage. Although it is challenging but an advances in molecular biomarkers and methods, early detection and diagnosis of cancer could be possible. The various genomic and proteomic tools are being used for identification of molecular signatures like genetic, epigenetic changes in gene expressions and protein expression. These approaches may help to detect risk of cancer and monitor therapy. Molecular diagnosis unravels different changes that occur during the transformation of a normal to tumour cells and capture information as expression patterns. Molecular techniques such as real-time PCR, DNA sequencing and microarrays being used extensively for early diagnosis of cancer. This chapter summarizes various techniques and molecular biomarkers for early diagnosis of cancer, which would help to predict cancer and development of new-targeted therapies.
KeywordsMolecular diagnosis Cancer Gene qPCR DNA sequencing
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