Advertisement

Plasmacytoma/Multiple Myeloma

  • Shantha AmrithEmail author
  • Stephanie Ming Young
  • Eric Ting
  • Bingcheng Wu
  • Min En Nga
  • Gangadhara Sundar
Chapter

Abstract

Plasmacytoma is a descriptive term applied to tumours consisting of plasma cells. International Myeloma Working Group has described three types, solitary, extramedullary and multiple plasmacytoma. Solitary is involvement of a single bone, extramedullary is a localized collection of plasma cells in the soft tissue at an extraskeletal site such as orbit, whereas multiple involves many bones. They all lack systemic involvement. When there is a systemic plasma cell disorder, it is called multiple myeloma. The incidence of plasmacytoma in the orbits is very rare, and rarer still is an orbital mass as a presenting feature in multiple myeloma.

Further Reading

  1. 1.
    Adkins JW, Shields JA, Shields CL, Eagle RC Jr, Flanagan JC, Campanella PC. Plasmacytoma of the eye and orbit. Int Ophthalmol. 1997;20:339–43.CrossRefGoogle Scholar
  2. 2.
    Lazaridou MN, Micallef-Eynaud P, Hanna IT. Soft tissue plasmacytoma of the orbit as part of the spectrum of multiple myeloma. Orbit. 2007;26:315–8.CrossRefPubMedGoogle Scholar
  3. 3.
    Sharma A, Kaushal M, Chaturvedi NK, Yadav R. Cytodiagnosis of multiple myeloma presenting as orbital involvement: a case report. Cyto J. 2006;10:3–19.Google Scholar

Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Shantha Amrith
    • 1
    • 2
    Email author
  • Stephanie Ming Young
    • 1
    • 2
  • Eric Ting
    • 3
    • 4
    • 5
  • Bingcheng Wu
    • 6
  • Min En Nga
    • 6
    • 7
  • Gangadhara Sundar
    • 1
    • 2
  1. 1.Department of OphthalmologyNational University HospitalSingaporeSingapore
  2. 2.Department of OphthalmologyYong Loo Lin School of Medicine, National University of SingaporeSingaporeSingapore
  3. 3.Department of Diagnostic ImagingNational University HospitalSingaporeSingapore
  4. 4.Department of Diagnostic ImagingYong Loo Lin School of Medicine, National University of SingaporeSingaporeSingapore
  5. 5.Advanced Medicine ImagingSingaporeSingapore
  6. 6.Department of PathologyNational University HospitalSingaporeSingapore
  7. 7.Department of PathologyYong Loo Lin School of Medicine, National University of SingaporeSingaporeSingapore

Personalised recommendations