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Lacrimal Sac Inverted Papilloma

  • Shantha AmrithEmail author
  • Stephanie Ming Young
  • Eric Ting
  • Bingcheng Wu
  • Min En Nga
  • Gangadhara Sundar
Chapter

Abstract

Inverted papilloma (IP), as the name suggests, is coined from the histological appearance of the epithelium inverting into the stroma. It is usually unilateral, with a male preponderance. Although it is more common in the sixth and seventh decades of life, isolated cases have been reported in the paediatric age group. Majority of the papillomas originate from the mucosal lining of the sino-nasal tract, occurring commonly in the ethmoids, lateral wall of the nasal fossa and the maxillary sinus. IP may arise primarily from the nasolacrimal duct (NLD) and the lacrimal sac, as they have similar mucosal lining. NLD and the lacrimal sac may be affected secondarily due to extension from the adjacent nasal mucosa or sinuses. Early detection gives the best chance of cure. High index of suspicion can lead to diagnosis during an unsuspected DCR, when the lacrimal sac epithelium is abnormal. An endoscopic resection, in collaboration with an otolaryngologist, may be the best approach on such cases.

Further Reading

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    Macdonald MR, Le KT, Freeman J, et al. A majority of inverted sinonasal papillomas carries Epstein-Barr virus genomes. Cancer. 1995;75:2307–12.CrossRefPubMedGoogle Scholar
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    Raemdonck TYE, VanDen Broecke CM, Claerhout I, Decock CE. Inverted papilloma arising primarily from the lacrimal sac. Orbit. 2009;28(2–3):181–4.CrossRefPubMedGoogle Scholar
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    Sundar G. Tumors of the lacrimal drainage system. In: Ali MJ, editor. Principles and practice of lacrimal surgery. New Delhi: Springer; 2018.Google Scholar
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    Walijee Z, Berry S, Quine S, Lane C, Morris DS, Bowman B. Inverted papilloma originating primarily from the nasolacrimal duct: a case report and review of the pertinent literature. Case Rep Otolaryngol. 2015;2015:123694.PubMedPubMedCentralGoogle Scholar
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    Woodcock M, Mollan SP, Harrison D, Taylor D, Lecuona K. Mitomycin C in the treatment of a Schneiderian (inverted) papilloma of the lacrimal sac. Int Ophthalmol. 2010;30(3):303–5.CrossRefPubMedGoogle Scholar

Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Shantha Amrith
    • 1
    • 2
    Email author
  • Stephanie Ming Young
    • 1
    • 2
  • Eric Ting
    • 3
    • 4
    • 5
  • Bingcheng Wu
    • 6
  • Min En Nga
    • 6
    • 7
  • Gangadhara Sundar
    • 1
    • 2
  1. 1.Department of OphthalmologyNational University HospitalSingaporeSingapore
  2. 2.Department of OphthalmologyYong Loo Lin School of Medicine, National University of SingaporeSingaporeSingapore
  3. 3.Department of Diagnostic ImagingNational University HospitalSingaporeSingapore
  4. 4.Department of Diagnostic ImagingYong Loo Lin School of Medicine, National University of SingaporeSingaporeSingapore
  5. 5.Advanced Medicine ImagingSingaporeSingapore
  6. 6.Department of PathologyNational University HospitalSingaporeSingapore
  7. 7.Department of PathologyYong Loo Lin School of Medicine, National University of SingaporeSingaporeSingapore

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