Examinations for Diagnosis
Various diagnostic methods for Hirschsprung’s disease are available. In radiography, a sudden widening of the caliber at the transition zone, called a “caliber change,” is a very important finding for diagnosis of Hirschsprung’s disease as well as for predicting the length of bowel to be surgically resected. A motility study for the recto-anal inhibitory reflex is also an important diagnostic procedure. High-resolution manometry is a novel but increasingly popular method of measuring the intraluminal pressure activity. Confocal laser endomicroscopy is the newest diagnostic tool and is capable of visualizing the enteric nervous system and may provide an alternative to intraoperative histopathological diagnosis in the near future. We herein describe diagnostic examination methods, radiographic procedures, and motility studies currently available for diagnosing and surgically treating Hirschsprung’s disease.
- 5.Sarin YK, Raj P, Thakkar N. Perils of total colonic aganglionosis presenting in neonatal age. J Neonat Surg. 2014;3:28.Google Scholar
- 14.de Lorijn F, Kremer LC, Reitsma JB, Benninga MA. Diagnostic tests in Hirschsprung disease: a systematic review. J Pediatr Gastroenterol Nutr. 2006;42:496–505. https://doi.org/10.1097/01.mpg.0000214164.90939.92.CrossRefPubMedGoogle Scholar