Benign Diseases of the Ovary

  • David Suster
  • Martina Z. Liu
  • Douglas I. LinEmail author


In surgical pathology, an understanding of the normal ovarian anatomy and the range of nonneoplastic lesions of the ovary is essential during the examination of gynecological specimens. Pathologists routinely evaluate nonneoplastic adult ovaries as components of (1) hysterectomy procedures for uterine leiomyomata, uterine prolapse, vaginal bleeding, or gynecological cancer and (2) risk-reducing prophylactic salpingo-oophorectomy, with the primary goals of excluding ovarian malignancy and/or determining whether the ovary is the source of hormone production driving uterine cancer. In these scenarios, with the exception of endometriosis, ovarian infection, or a hormone-producing lesion, any incidental nonneoplastic lesion encountered in the ovary is likely not of clinical significance. However, another frequently encountered scenario is examination of the ovary via biopsy, cystectomy, or excision for a specific purpose, including ovarian enlargement, cyst formation, masses, torsion, infection, infertility, or ectopic pregnancy, in which the ovary is submitted for evaluation for a clinical or radiological reason. Each of these settings requires the pathologist to have knowledge of the normal ovarian anatomy, the histology, and the range of nonneoplastic lesions of the ovary in order to guide the obstetrician-gynecologist or gynecologic oncologist to the appropriate treatment and follow-up.


Ovary Benign Nonneoplastic Anatomy Histology 


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Copyright information

© Science Press & Springer Nature Singapore Pte Ltd.  2019

Authors and Affiliations

  • David Suster
    • 1
  • Martina Z. Liu
    • 2
  • Douglas I. Lin
    • 3
    Email author
  1. 1.Department of PathologyBeth Israel Deaconess Medical CenterBostonUSA
  2. 2.Brigham and Women’s HospitalBostonUSA
  3. 3.Foundation Medicine, Inc.CambridgeUSA

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