Aggravation of Asthma by Cold, Fatigue, Stress, or Discontinuation of Medicines: What Should We Measures and Prevents Worse of Asthma Control Induced by the Aggravation of the Environmental Hygiene and/or the Stopping Medicine?

  • Toshiyuki KoyaEmail author
  • Takashi Hasegawa
Part of the Respiratory Disease Series: Diagnostic Tools and Disease Managements book series (RDSDTDM)


Bronchial asthma can be exacerbated by many factors, the most important of which are airway infection, including upper respiratory tract infection. However, in times of disaster, changes in temperature (cold air), fatigue, mental stress, and discontinuation of medicines can also exacerbate asthma and cause acute symptoms. In such situations, clinicians often encounter the exacerbation of asthma symptoms by cold air, which is thought to affect the immune and nervous systems through contact with the airway mucosa. Deterioration of asthma due to fatigue and mental stress is also common. In particular, evacuation after disasters causes great mental stress, as do loss of home, uncertainty about the unpredictable future, etc. Medical system collapse and subsequent discontinuation of drug treatment are serious problems for patients with chronic disease. In particular, inhaled corticosteroids are critical medicines for asthma patients. Maintaining a system of drug supply after major disasters is a challenge in Japan, which experiences many natural disasters, including earthquakes.


Cold air Physical fatigue Mental stress Inhaled corticosteroid Asthma death 


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© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  1. 1.Department of Respiratory Medicine and Infectious DiseasesNiigata University Graduate School of Medical and Dental SciencesNiigata CityJapan
  2. 2.Department of General MedicineNiigata University Medical and Dental HospitalNiigata CityJapan

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