The Visual Field Defects of Leber’s Disease

  • Xiaojing Pan
  • Ning Fan
  • Xuyang Liu
Part of the Advances in Visual Science and Eye Diseases book series (AVSED, volume 2)


Leber’s hereditary optic neuropathy (LHON) is a maternal genetic disorder caused by point mutations of mitochondrial DNA (mtDNA). Visual field damage in LHON is mostly central defects of various sizes and shapes. In this section, several selected cases of the mutation of the same mtDNA are analyzed, and the pathogenesis of LHON is discussed at the molecular level.


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Copyright information

© Springer Nature Singapore Pte Ltd. & People's Medical Publishing House, PR of China 2019

Authors and Affiliations

  • Xiaojing Pan
    • 1
  • Ning Fan
    • 2
  • Xuyang Liu
    • 3
    • 2
  1. 1.Shandong Eye Institute, Qingdao Eye HospitalQingdaoChina
  2. 2.Shenzhen Eye Hospital, Shenzhen UniversityShenzhenChina
  3. 3.Xiamen Eye Center of Xiamen UniversityXiamenChina

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