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The Clinical and Genetic Analysis of Stargardt’s Disease

  • Ning Fan
  • Xuyang Liu
  • Jiantao Wang
Chapter
Part of the Advances in Visual Science and Eye Diseases book series (AVSED, volume 2)

Abstract

Stargardt disease is also called juvenile macular degeneration, and its main ocular manifestations are bilateral vision decrease and central visual field defects. Three cases are discussed in this section, among which the patient was a descendant from consanguineous marriage in two cases. This phenomenon highlights the importance of the family planning work.

References

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    Riveiro-Alvarez R, Lopez-Martinez M-A, Zernant J, et al. Outcome of ABCA4 disease-associated alleles in autosomal recessive retinal dystrophies: retrospective analysis in 420 Spanish families. Ophthalmology. 2013;120(11):2332–7.CrossRefGoogle Scholar
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    Auricchio A, Trapani I, Allikmets R. Gene therapy of ABCA4-associated diseases. Cold Spring Harb Perspect Med. 2015;5(5):a017301.CrossRefGoogle Scholar

Copyright information

© Springer Nature Singapore Pte Ltd. & People's Medical Publishing House, PR of China 2019

Authors and Affiliations

  • Ning Fan
    • 1
  • Xuyang Liu
    • 2
    • 1
  • Jiantao Wang
    • 1
  1. 1.Shenzhen Eye Hospital, Shenzhen UniversityShenzhenChina
  2. 2.Xiamen Eye Center of Xiamen UniversityXiamenChina

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