Prolonged Intermittent Renal Replacement Therapy in Pediatric AKI
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Acute kidney injury in children in intensive care is often secondary to shock and multi-organ dysfunction syndrome. These children are often on inotropes, are hypotensive, and are fluid overloaded. Continuous renal replacement therapy (CRRT) often used in developed world requires expertise, expensive machinery, consumables, trained staff and is labor intensive. Sustained low-efficiency dialysis (SLED) refers to intermittent renal replacement therapy over an extended period of time. There is now evidence in favor of this therapy especially in adults, with few case series from pediatric literature.
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