Intracranial and Intraocular Pressure-Related Diseases
The optic nerve is the only pair of cranial nerves that pass through three sealing containers with pressure. First, the retinal ganglion cell bodies and its gathering of the axons belong to the ocular container. Then, the rest part of the axons is surrounded by cerebrospinal fluid along its pathway, until into the third container, the intracranial container. The connection between the first two containers is called the laminar cribrosa, which is the part of the sclera that is pierced by the axons. The intracranial container is a bone structure without space to expand. So, the intracranial pressure change can severely impair the neuro structures. At the same time, the ocular container is constructed with compact fiber tissues, also with no space to expand.
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