Optic Nerve Sheath Fenestration: A Way to Balance the Trans-Laminar Cribrosa Pressure Difference?

  • Zhen Li
  • Xuxiang Zhang
  • Dachuan Liu
  • Ningli WangEmail author
Part of the Advances in Visual Science and Eye Diseases book series (AVSED, volume 1)


Papilledema is defined as a secondary edema of the optic disc caused by the increased intracranial pressure [1]. A variety of intracranial diseases will lead to increased intracranial pressure, such as intracranial space-occupying lesion, various forms of hydrocephalus, intracranial infection, cerebral venous sinus thrombosis, and idiopathic intracranial hypertension (IIH) (Fig. 28.1).


  1. 1.
    Whiting AS, Johnson LN. Papilledema: clinical clues and differential diagnosis. Am Fam Physician. 1992;45(3):1125–34.PubMedGoogle Scholar
  2. 2.
    Tso MO, Hayreh SS. Optic disc edema in raised intracranial pressure. III. A pathologic study of experimental papilledema. Arch Ophthalmol. 1977;95(8):1448–57.CrossRefGoogle Scholar
  3. 3.
    Wirtschafter JD, Rizzo FJ, Smiley BC. Optic nerve axoplasm and papilledema. Surv Ophthalmol. 1975;20(3):157–89.CrossRefGoogle Scholar
  4. 4.
    Luo Y, Tian X, Wang X. Diagnosis and treatment of cerebral venous thrombosis: a review. Front Aging Neurosci. 2018;10:2.CrossRefGoogle Scholar
  5. 5.
    Coutinho JM, Stam J. A rare cause of thunderclap headache. BMJ. 2011;341:c6054.CrossRefGoogle Scholar

Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Zhen Li
    • 1
  • Xuxiang Zhang
    • 1
  • Dachuan Liu
    • 1
  • Ningli Wang
    • 2
    • 3
    Email author
  1. 1.Department of OphthalmologyXuanwu Hospital, Capital Medical UniversityBeijingChina
  2. 2.Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren HospitalCapital Medical UniversityBeijingChina
  3. 3.Beijing Ophthalmology & Visual Sciences Key LaboratoryBeijingChina

Personalised recommendations