Neuroanesthesia and Coexisting Genetic Problems

  • Srilata Moningi
  • Subodh Raju


There are ample number of neurosurgical conditions that have associated genetic disorders. Neurosurgical conditions include craniosynostosis, craniopagus twins, and craniovertebral anomalies like atlantoaxial instability, meningomyelocele, and other neural tube defects. Some of the commonly associated genetic disorders are Down’s syndrome, Klippel-Feil syndrome, Goldenhar syndrome, Apert syndrome, and Muenke syndrome. Findings vary from airway changes to bony changes and from cardiac to renal anomalies. Depending upon the type and severity of the lesions, possible complications may vary from neurologic sequelae, respiratory complications, ventilatory and weaning issues, coagulation abnormalities, positioning problems to common problems like venous air embolism, temperature and acid-base changes, and fluid and electrolyte abnormalities to postoperative pain management. Dedicated neuroanesthesia care is the key to a successful perioperative management and positive outcome of these patients.


Neurosurgery Genetics Disorders Neuroanesthesia Perioperative Complications Management Outcome 


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Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Srilata Moningi
    • 1
  • Subodh Raju
    • 2
  1. 1.Department of AnesthesiaNizam’s Institute of Medical SciencesHyderabadIndia
  2. 2.Department of NeurosurgeryApollo HospitalsHyderabadIndia

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