Microarray Gene Expression Analysis Using Fuzzy Logic (MGA-FL)

  • Daksh KhannaEmail author
  • Tanupriya Choudhury
  • A. Sai Sabitha
  • Nguyen Gia Nhu
Conference paper
Part of the Advances in Intelligent Systems and Computing book series (AISC, volume 755)


Fuzzy logic is an arrangement to sort with registering in light for “degrees of truth” instead of the standard thing “genuine or false” (1 or 0) Boolean logic. A Deoxyribonucleic corrosive (DNA) microarray (in like manner normally known as Deoxyribonucleic Acid chip or bio-chip) is a collection of small DNA-spots annexed to a hard surface (Mukhopadhyay et al., Analysis of microarray data using multiobjective variable string length genetic fuzzy clustering, 2009) [1]. DNA microarrays are used to gage the explanation hierarchy of significant amounts of characteristics in the meantime or to geno-type distinctive areas of a genome. Each Deoxyribonucleic Acid spot consist of micro-moles (appx. 11 mol) of a particular Deoxyribonucleic Acid progression, justified as tests (or writers or oligos). It can be a small territory of a quality or other DNA segment which is used to hybridize a complementary DNA/complementary RNA (in like manner called antagonistic to identify Ribonucleic Acid) test (called centre) under high-stringency terms. Test object hybridization is normally recognized and acquired through distinguishing proof of “fluorophore-, silver-, or chemiluminescence”—named centres to choose relatively abundant nucleic destructive game plans for the goal. The principal nucleic destructive displays were expansive scale groups around 9 cm × 12 cm and the fundamental modernized picture based examination was circulated in 1981. Microarray information investigation includes a few unmistakable advances. Changing any of the means will change the result of the examination, so the MAQC Project was made to recognize an arrangement of standard procedures (Mukhopadhyay et al., Analysis of microarray data using multiobjective variable string length genetic fuzzy clustering, 2009) [1], (Li, International Seminar on Future BioMedical Information Engineering, 2008) [4]. Organizations exist that utilization the MicroArray/Sequencing Quality Control (MAQC) conventions to play out a total examination. The human genome contains roughly 21,000 qualities. At any given minute, each of our cells has some mix of these qualities turned on, and others are killed (Pujari, Data Mining Techniques, 2001) [2].


Bioinformatics Microarray Fuzzy logic Association Clustering 


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Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Daksh Khanna
    • 1
    Email author
  • Tanupriya Choudhury
    • 2
  • A. Sai Sabitha
    • 1
  • Nguyen Gia Nhu
    • 3
  1. 1.Amity UniversityNoidaIndia
  2. 2.University of Petroleum and Energy StudiesDehradunIndia
  3. 3.Duy Tan UniversityDa NangVietnam

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