Coagulopathy in Liver Disease

  • Naresh Shanmugam
  • Vimal Kumar


Liver plays an important role in coagulation. Apart from von Willebrand factor, all the other clotting factors are synthesized by the liver. Coagulopathy in liver disease is a reflection of synthetic liver failure. The normal coagulation cascade is outlined in Fig. 5.1. Always look for superimposed causes of coagulopathy such as vitamin K deficiency, infections, and renal failure.

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© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Naresh Shanmugam
    • 1
  • Vimal Kumar
    • 2
  1. 1.Department of Paediatric Liver, GI and NutritionInstitute of Advanced Paediatrics, Dr. Rela Institute and Medical CentreChennaiIndia
  2. 2.Department of Paediatric Haematology, Oncology, Blood and Marrow TransplantationInstitute of Advanced Paediatrics, Gleneagles Global Health CityChennaiIndia

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