Blood Product Usage in Liver Transplantation

  • Deepti Sachan


Liver transplantation has emerged as an increasingly successful treatment for patients with end-stage liver disease (ESLD). The operative procedure is extensive, complex and technically challenging, with multiple vascular transections and anastomoses. Historically, liver transplantation was associated with massive blood loss and requires maximum component support amongst all organ transplants. Over the last few decades, with the continuous improvements in surgical techniques, use of pharmacological alternatives of blood and availability of potent immunosuppressive agents, there are remarkable improvements in survival outcomes of liver transplantation. General instructions of blood products handling and storage are outlined in Table 25.1.

Further Reading

  1. 1.
    Yusava N, Niwa N, Kimuara S, Tsuji H, Yurugi K, Egawa H, et al. Intraoperative blood loss during living donor liver transplantation: an analysis of 635 recipients at a single center. Transfusion. 2005;45:879–84.CrossRefGoogle Scholar
  2. 2.
    Rajesh K, Harsh S, Amarjit K. Effects of prestorage leukoreduction on the rate of febrile nonhemolytic transfusion reactions to red blood cells in a tertiary care hospital. Ann Med Health Sci Res. 2015;5:185–8.CrossRefGoogle Scholar
  3. 3.
    Wu Y, Zou S, Cable R, et al. Direct assessment of cytomegalovirus transfusion-transmitted risks after universal leukoreduction. Transfusion. 2010;50:776–86.CrossRefGoogle Scholar
  4. 4.
    Narvios AB, Lichtiger B. Bedside leukoreduction of cellular blood components in preventing cytomegalovirus transmission in allogeneic bone marrow transplant recipients: a retrospective study. Haematologica. 2001;86:749–52.PubMedGoogle Scholar

Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Deepti Sachan
    • 1
  1. 1.Department of Transfusion MedicineDr. Rela Institute and Medical CentreChennaiIndia

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