Status of Arsenic Toxicity in the World

  • Mustafeez Mujtaba BabarEmail author
  • Aneela Tariq


Arsenic (As) is a major environmental contaminant that affects the plant, animal, and human life. It is obtained from the earth’s crust and finds its use in industrial, cosmetic, agricultural, and health sectors. Though due to the medical concerns, its use has decreased, yet it continues to be bioavailable in different forms. Released through geological and anthropogenic activities, it presents to be a major risk to the human population. The current chapter reviews the role of As as a potential environmental contaminant and its effect as a carcinogen and toxin to the humans. Various sources of introduction of As into the environment are then discussed. A comprehensive review of the geographical patterns of As occurrence in environmental samples has then been provided along with the interventional strategies that can be employed to decrease the effects of As toxicity.


Arsenic toxicity Global perspective Geographical distribution Arsenicosis Arsenic poisoning 






As (III)

Trivalent arsenic

As (V)

Pentavalent arsenic


Agency for Toxic Substances and Disease Registry




Centers for Disease Control and Prevention


Cyclin-dependent kinases


Comprehensive Environmental Response, Compensation, and Liability Act








Department of Environment and Conservation


Dimethylarsinic acid


Deoxyribonucleic acid


Ecological Investigation Levels




Gross domestic product


Joint FAO-WHO Expert Committee on Food Additives






Limits of detection


Mitogen-activated protein kinases


Maximum Contaminant Level




Monosodium methanearsonate








Parts per billion


Potentially toxic elements


Reactive oxygen species


United Arab Emirates


United States


World Health Organization




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© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  1. 1.Shifa College of Pharmaceutical SciencesShifa Tameer-e-Millat UniversityIslamabadPakistan
  2. 2.Department of Physical Therapy, Faculty of Pharmaceutical and Allied Health SciencesShifa Tameer-e-Millat UniversityIslamabadPakistan

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