Endoscopic Management of Non-ampullary Duodenal Neoplasia

  • Moon Kyung Joo
  • Jong-Jae ParkEmail author


A portion of non-ampullary duodenal neoplasia including adenoma, adenocarcinoma, and neuroendocrine tumors are good candidates for endoscopic resection. Endoscopic mucosal resection (EMR) is a technically safe and feasible method for treatment of non-ampullary duodenal neoplasia. However, endoscopic submucosal dissection (ESD) is a technically challenging procedure even in experts of therapeutic endoscopy, and serious complications such as delayed bleeding or perforation may occur frequently. Successful ESD for non-ampullary duodenal neoplasia may be aided by various accessories or advanced skills including small-caliber-tip caps, tunneling techniques, and “push and peel-off technique.” However, more technical advances and clinical experiences are needed to improve the short- and long-term outcomes of ESD for non-ampullary duodenal neoplasia. For successful endoscopic resection, physicians should be familiar with the various instruments needed for the procedure and able to handle them skillfully.


Duodenum Neoplasia Endoscopic mucosal resection Endoscopic submucosal dissection 


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Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  1. 1.Department of Internal MedicineKorea University College of MedicineSeoulSouth Korea

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