Subepithelial tumors (SETs) in the gastrointestinal tract are often incidentally found during endoscopic examinations, and the incidence of SETs has gradually increased. Endoscopic ultrasonography (EUS) is a good diagnostic modality for differential diagnosis of SETs, but a definite diagnosis cannot be made based on EUS features alone in some cases. Periodic follow-up endoscopy and EUS remain the recommended management strategies; however, this strategy involves issues related to patient compliance, cost-effectiveness, and the risk associated with repeated endoscopic procedures and delayed diagnosis of malignancy. Endoscopic resection of the SETs is another modality to treat them as well as to obtain tissue specimens for accurate histologic diagnosis. Here, various endoscopic techniques ranging from standard endoscopic submucosal resection to endoscopic full-thickness resection for SETs will be reviewed.
Lee DG, Kim GH, Park DY, et al. Endoscopic submucosal resection of esophageal subepithelial lesions using band ligation. Endoscopy. 2011;43:822–5.CrossRefGoogle Scholar
Lee KJ, Kim GH, Park DY, et al. Endoscopic resection of gastrointestinal lipomas: a single-center experience. Surg Endosc. 2014;28:185–92.CrossRefGoogle Scholar
Lee JS, Kim GH, Park DY, et al. Endoscopic submucosal dissection for gastric subepithelial tumors: a single-center experience. Gastroenterol Res Pract. 2015;2015:425469.PubMedPubMedCentralGoogle Scholar
Białek A, Wiechowska-Kozłowska A, Pertkiewicz J, et al. Endoscopic submucosal dissection for treatment of gastric subepithelial tumors (with video). Gastrointest Endosc. 2012;75:276–86.CrossRefGoogle Scholar
Li QL, Yao LQ, Zhou PH, et al. Submucosal tumors of the esophagogastric junction originating from the muscularis propria layer: a large study of endoscopic submucosal dissection (with video). Gastrointest Endosc. 2012;75:1153–8.CrossRefGoogle Scholar
Lee SH, Kim SJ, Lee TH, et al. Human applications of submucosal endoscopy under conscious sedation for pure natural orifice transluminal endoscopic surgery. Surg Endosc. 2013;27:3616–20.CrossRefGoogle Scholar