Pathology of Placenta

  • Pranab Dey


In this chapter various abnormalities of the placenta are discussed with illustrations such as abnormal adherence of placenta, infections, maternal and fetal circulatory disorders, and tumours of placenta. The gross abnormalities, histopathology features along with clinical significance of these lesions are mentioned with microphotographs.


Placenta percreta Placenta accreta Placenta increta Chorioamnionitis Funisitis Placental tuberculosis Plasmodium infection Maternal floor infract Perivillous fibrin deposition Chorangiosis Rh incompatibility Squamous metaplasia of membrane Pre-eclampsia Chorangioma Allantoic duct Acute leukaemia Single umbilical artery 

Suggested Reading

  1. Abramowsky CR, Gutman J, Hilinski JA. Mycobacterium tuberculosis infection of the placenta: a study of the early (innate) inflammatory response in two cases. Pediatr Dev Pathol. 2012;15(2):132–6.CrossRefGoogle Scholar
  2. Chen A, Roberts DJ. Placental pathologic lesions with a significant recurrence risk - what not to miss! APMIS. 2017; Scholar
  3. Doritchamou JYA, Akuffo RA, Moussiliou A, Luty AJF, Massougbodji A, Deloron P, Tuikue Ndam NG. Submicroscopic placental infection by non-falciparum Plasmodium spp. PLoS Negl Trop Dis. 2018;12(2):e0006279.CrossRefGoogle Scholar
  4. Fan M, Skupski DW. Placental chorioangioma: literature review. J Perinat Med. 2014;42(3):273–9.CrossRefGoogle Scholar
  5. Naeye RL. Maternal floor infarction. Hum Pathol. 1985;16:823–8.CrossRefGoogle Scholar
  6. Redline RW, Faye-Petersen O, et al. Amniotic infection syndrome: nosology and reproducibility of placental reaction patterns. Pediatr Dev Pathol. 2003;6:435–48.CrossRefGoogle Scholar
  7. Salmani D, Purushothaman S, Somashekara SC, Gnanagurudasan E, Sumangaladevi K, Harikishan R, Venkateshwarareddy M. Study of structural changes in placenta in pregnancy-induced hypertension. J Nat Sci Biol Med. 2014;5(2):352–5.CrossRefGoogle Scholar
  8. Silver RM, Barbour KD. Placenta accreta spectrum: accreta, increta, and percreta. Obstet Gynecol Clin North Am. 2015;42(2):381–402.CrossRefGoogle Scholar
  9. Stanek J. Chorangiosis of chorionic villi: what does it really mean? Arch Pathol Lab Med. 2016;140(6):588–93.CrossRefGoogle Scholar
  10. Wortman AC, Alexander JM. Placenta accreta, increta, and percreta. Obstet Gynecol Clin N Am. 2013;40(1):137–54.CrossRefGoogle Scholar

Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Pranab Dey
    • 1
  1. 1.Post Graduate Institute of Medical Education and Research (PGIMER)ChandigarhIndia

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