Talking Through Chemical Languages: Quorum Sensing and Bacterial Communication

  • Mohini Mohan Konai
  • Geetika Dhanda
  • Jayanta HaldarEmail author


Bacteria constitute a large domain of prokaryotic microorganisms which have been cohabiting with us for a very long time. Nevertheless, understanding them is a magnificent task. Communication among bacteria, both inter-species and intra-species constitutes a highly specific but complicated process known as ‘Quorum sensing’. Many essential group behaviours (such as bioluminescence, virulence, swarming, nodulation, biofilm formation and many more) in bacterial population are guided by quorum sensing which involves production of molecules, acting as signals. Recognition of the signals results in gene expression, which ultimately regulates the collective behaviour beneficial for bacterial survival. The signalling molecules are different for Gram-positive and Gram-negative bacteria. In this chapter, we have discussed various classes of signalling molecules, their production, recognition and signal transduction.


Acyl homoserine lactone Autoinducing peptide Signal production Signal recognition Signal transduction Quorum sensing 



N-(3-hydroxy- 7-cis-tetradecenoyl)-L-homoserine lactone,


N-3-oxo-decanoyl-L-homoserine lactone,


N-3-oxo-dodecanoyl-L-homoserine lactone,


N-3-oxo-hexanoyl-L- homoserine lactone,


N-3-oxo-octanoyl-L-homoserine lactone,


N-(7-cis-tetradecenoyl)-L-homoserine lactone,


Acyl carrier protein,


Accessory gene regulator,


Acyl homoserine lactone,


Autoinducer 2,


Autoinducing peptide,


Antimicrobial resistance,


N-decanoyl-L-homoserine lactone,


N-dodecanoyl-L-homoserine lactone,


N-tetradecanoyl-L-homoserine lactone,


N-butanoyl-L-homoserine lactone,


N-hexanoyl-L-homoserine lactone,


N-octanoyl-L-homoserine lactone,


Cholera autoinducer 1,






Diffusible signal factor,


Histidine protein kinase,


Homoserine lactone,


Pseudomonas quinolone signal


Quorum regulatory,


Quorum sensing,


response regulator,


S- adenosylmethionine


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Copyright information

© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  • Mohini Mohan Konai
    • 1
  • Geetika Dhanda
    • 1
  • Jayanta Haldar
    • 1
    Email author
  1. 1.Antimicrobial Research Laboratory, New Chemistry UnitJawaharlal Nehru Centre for Advanced Scientific ResearchBengaluruIndia

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