Quorum Sensing and Its Inhibition: Biotechnological Applications

  • Vipin Chandra KaliaEmail author
  • Jyotsana Prakash
  • Shikha Koul
  • Subhasree Ray


Microorganisms have long been used in various areas of biotechnology. In the recent times what has gained fascination is the communication among microbes, known as Quorum sensing (QS). Fascinating information has been generated on understanding the significance of QS, and its inhibition (QSI), especially in plant, animal and human pathogenesis. Focus has now shifted on exploiting QS and QSIs for biotechnological applications in designing: (i) genetic circuits for producing novel products, (ii) biosensors, (iii) molecules for cancer therapy, etc. Here, we cover a few applications in Health, Agriculture, Aquaculture, Energy and Bioremediation sectors.


Aquaculture Bioenergy Biofouling Bioremediation Cancer Food Health Plants Pathogens Quorum sensing 











Acylhomoserine lactone




Autoinducing peptides








N-butanoyl-L-homoserine lactone




Homoserine lactone



This work was supported by Brain Pool grant (NRF-2018H1D3A2001746) by National Research Foundation of Korea (NRF) to work at Konkuk University (VCK).


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Copyright information

© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  • Vipin Chandra Kalia
    • 1
    Email author
  • Jyotsana Prakash
    • 2
    • 3
  • Shikha Koul
    • 2
    • 3
  • Subhasree Ray
    • 2
    • 3
  1. 1.Molecular Biotechnology Lab, Department of Chemical EngineeringKonkuk UniversitySeoulRepublic of Korea
  2. 2.Microbial Biotechnology and GenomicsCSIR – Institute of Genomics and Integrative Biology (IGIB), Delhi University CampusDelhiIndia
  3. 3.Academy of Scientific & Innovative Research (AcSIR)New DelhiIndia

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