Advertisement

Neuropharmacology of Chamomiles

  • Amritpal Singh Saroya
  • Jaswinder Singh
Chapter

Abstract

The synonym is M. chamomilla L., and M. recutita is commonly known as German chamomile and true chamomile (Kreitmair 1951). The plant is native to Afghanistan, Europe and Iran (Formentini and Rocchi 1961). The dried flower heads are utilized in ethnomedicine for preparation of tea with antispasmodic (spasmolytic) and sedative properties (Viola et al. 1995).

References

  1. Amsterdam JD, Li Y, Soeller I, Rockwell K, Mao JJ, Shults J. A randomized, double-blind, placebo-controlled trial of oral Matricaria recutita (chamomile) extract therapy for generalized anxiety disorder. J Clin Psychopharmacol. 2009;29:378–82.CrossRefPubMedPubMedCentralGoogle Scholar
  2. Amsterdam JD, Shults J, Soeller I, Mao JJ, Rockwell K, Newberg AB. Chamomile (Matricaria recutita) may provide antidepressant activity in anxious, depressed humans: an exploratory study. Altern Ther Health Med. 2012;18:44–9.PubMedPubMedCentralGoogle Scholar
  3. Can OD, Demir Özkay U, Kıyan HT, Demirci B. Psychopharmacological profile of Chamomile (Matricaria recutita L.) essential oil in mice. Phytomedicine. 2012;19:306–10.CrossRefPubMedPubMedCentralGoogle Scholar
  4. Carnat A, Carnat AP, Fraisse D, Ricoux L, Lamaison JL. The aromatic and polyphenolic composition of Roman chamomile tea. Fitoterapia. 2004;75:32–8.CrossRefPubMedPubMedCentralGoogle Scholar
  5. Chandrashekhar VM, Ranpariya VL, Ganapaty S, Parashar A, Muchandi AA. Neuroprotective activity of Matricaria recutita Linn against global model of ischemia in rats. J Ethnopharmacol. 2010;127:645–51.CrossRefPubMedGoogle Scholar
  6. Formentini L, Rocchi B. Contribution to the pharmacopoeia. Proposed monograph on Matricaria chamomilla. Boll Chim Farm. 1961;100:37–9.PubMedGoogle Scholar
  7. Grigson G. The Englishman’s Flora. Oxford: Helicon Publishing Ltd; 1996.Google Scholar
  8. Keefe JR, Mao JJ, Soeller I, Li QS, Amsterdam JD. Short-term open-label chamomile (Matricaria chamomilla L.) therapy of moderate to severe generalized anxiety disorder. Phytomedicine. 2016;23:1699–705.CrossRefPubMedPubMedCentralGoogle Scholar
  9. Kreitmair H. Matricaria chamomilla L., the true chamomile. Pharmazie. 1951;6:65–6.PubMedGoogle Scholar
  10. Luppold E. Matricaria chamomilla-an old and new medicinal plant. Pharm Unserer Zeit. 1984;13:65–70.CrossRefPubMedPubMedCentralGoogle Scholar
  11. Mabey R. Flora Britannica. London: Sinclair-Stevenson; 1996.Google Scholar
  12. Mao JJ, Xie SX, Keefe JR, Soeller I, Li QS, Amsterdam JD. Long-term chamomile (Matricaria chamomilla L.) treatment for generalized anxiety disorder: a randomized clinical trial. Phytomedicine. 2016;23:1735–42.CrossRefPubMedPubMedCentralGoogle Scholar
  13. Ranpariya VL, Parmar SK, Sheth NR, Chandrashekhar VM. Neuroprotective activity of Matricaria recutita against fluoride-induced stress in rats. Pharm Biol. 2011;49:696–701.CrossRefPubMedGoogle Scholar
  14. Viola H, Wasowski C, Levi de Stein M, Wolfman C, Silveira R, Dajas F, Medina JH, Paladini AC. Apigenin, a component of Matricaria recutita flowers, is a central benzodiazepine receptors-ligand with anxiolytic effects. Planta Med. 1995;61:213–6.CrossRefPubMedGoogle Scholar

Copyright information

© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  • Amritpal Singh Saroya
    • 1
  • Jaswinder Singh
    • 2
  1. 1.Herbal ConsultantMohaliIndia
  2. 2.Department of PharmacologySri Guru Ram Das Institute of Medical ScienceAmritsarIndia

Personalised recommendations