Medicinal Herbs Used in Herbal Medicine for Neurological Disorders

  • Amritpal Singh Saroya
  • Jaswinder Singh


A. julibrissin is native to Asia and popularly known as Persian silk tree. In traditional Chinese medicine, it is used to treat anxiety and depression. The plant is reported to contain flavonoids (Wei and Guo 2015).


  1. Ahmad VU, Bano S. Chemical examination of Nepeta hindostana (Roth) Haines the structure of nepeticin. Tetrahedron Lett. 1981;22:1714–8.CrossRefGoogle Scholar
  2. Ahmad J, Siddiqi TO, Arora RB. Badranjboya: an important drug of Unani system of medicine. J Res Educ Indian Med. 1986a;5(3–4):5–10.Google Scholar
  3. Ahmad VU, Bano S, Bano N. A triterpene acid from Nepeta hindostana. Phytochemistry. 1986b;25:1487–8.CrossRefGoogle Scholar
  4. An HM, Li GW, Lin C, Gu C, Jin M, Sun WX, Qiu MF, Hu B. Acorus tatarinowii Schott extract protects PC12 cells from amyloid-beta induced neurotoxicity. Pharmazie. 2014;69:391–5.PubMedPubMedCentralGoogle Scholar
  5. Cheon SM, Jang I, Lee MH, Kim DK, Jeon H, Cha DS. Sorbus alnifolia protects dopaminergic neurodegeneration in Caenorhabditis elegans. Pharm Biol. 2017;55:481–6.CrossRefPubMedPubMedCentralGoogle Scholar
  6. Ching FP, Omogbai EK, Otokiti IO. Aqueous stem bark extract of Stereospermum kunthianum (Cham, Sandrine Petit) protects against generalized seizures in pentylenetetrazole and electro-convulsive models in rodents. Afr J Tradit Complement Altern Med. 2009;6:544–8.PubMedPubMedCentralGoogle Scholar
  7. Coetzee DD, López V, Smith C. High-mesembrine Sceletium extract (Trimesemine™) is a monoamine releasing agent, rather than only a selective serotonin reuptake inhibitor. J Ethnopharmacol. 2016;177:111–6.CrossRefPubMedGoogle Scholar
  8. De Prá SD, Ferro PR, Milioli AM, Rigo FK, Chipindo OJ, Camponogara C, Casoti R, Manfron MP, de Oliveira SM, Ferreira J, Trevisan G. Antinociceptive activity and mechanism of action of hydroalcoholic extract and dichloromethane fraction of Amphilophium crucigerum seeds in mice. J Ethnopharmacol. 2017;195:283–97.CrossRefPubMedGoogle Scholar
  9. Gericke N, Viljoen AM. Sceletium-a review update. J Ethnopharmacol. 2008;119:653–63.CrossRefPubMedGoogle Scholar
  10. Guzmán-Gutiérrez SL, Gómez-Cansino R, García-Zebadúa JC, Jiménez-Pérez NC, Reyes-Chilpa R. Antidepressant activity of Litsea glaucescens essential oil: identification of β-pinene and linalool as active principles. J Ethnopharmacol. 2012;143(2):673–9.CrossRefPubMedGoogle Scholar
  11. Guzmán-Gutiérrez SL, Reyes-Chilpa R, Jaime HB. Medicinal plants for the treatment of “nervios”, anxiety, and depression in Mexican traditional medicine. Rev Bras. 2014;24:591–608.Google Scholar
  12. Harvey AL, Young LC, Viljoen AM, Gericke NP. Pharmacological actions of the south African medicinal and functional food plant Sceletium tortuosum and its principal alkaloids. J Ethnopharmacol. 2011;137:1124–9.CrossRefPubMedGoogle Scholar
  13. Herrera-Arellano A, Jiménez-Ferrer E, Zamilpa A, Morales-Valdéz M, García-Valencia CE, Tortoriello J. Efficacy and tolerability of a standardized herbal product from Galphimia glauca on generalized anxiety disorder. A randomized, double-blind clinical trial controlled with lorazepam. Planta Med. 2007;73:713–7.CrossRefPubMedGoogle Scholar
  14. Herrera-Arellano A, Jiménez-Ferrer JE, Zamilpa A, García-Alonso G, Herrera-Alvarez S, Tortoriello J. Therapeutic effectiveness of Galphimia glauca vs. lorazepam in generalized anxiety disorder. A controlled 15-week clinical trial. Planta Med. 2012;78:1529–35.CrossRefPubMedPubMedCentralGoogle Scholar
  15. Herrera-Ruiz M, González-Cortazar M, Jiménez-Ferrer E, Zamilpa A, Alvarez L, Ramírez G, Tortoriello J. Anxiolytic effect of natural galphimines from Galphimia glauca and their chemical derivatives. J Nat Prod. 2006;69:59–61.CrossRefPubMedPubMedCentralGoogle Scholar
  16. Liao WP, Chen L, Yi YH, Sun WW, Gao MM, Su T, Yang SQ. Study of antiepileptic effect of extracts from Acorus tatarinowii Schott. Epilepsia. 2005;46:21–4.CrossRefPubMedGoogle Scholar
  17. Luz DA, Pinheiro AM, Silva ML, Monteiro MC, Prediger RD, Ferraz Maia CS, Fontes-Júnior EA. Ethnobotany, phytochemistry and neuropharmacological effects of Petiveria alliacea L. (Phytolaccaceae): a review. J Ethnopharmacol. 2016;185:182–201.CrossRefPubMedGoogle Scholar
  18. Makino Y, Kondo S, Nishimura Y, Tsukamoto Y, Huang ZL, Urade Y. Hastatoside and verbenalin are sleep-promoting components in Verbena officinalis. Sleep Biol Rhyt. 2009;7:211–7.CrossRefGoogle Scholar
  19. Marder M, Viola H, Wasowski C, Wolfman C, Waterman PG, Medina JH, Paladini AC. Cirsiliol and caffeic acid ethyl ester, isolated from Salvia guaranitica, are competitive ligands for the central benzodiazepine receptors. Phytomedicine. 1996;3:29–31.CrossRefPubMedGoogle Scholar
  20. Ojewole JA. Anticonvulsant activity of Hypoxis hemerocallidea Fisch. & C. A. Mey. (Hypoxidaceae) corm (‘African potato’) aqueous extract in mice. Phytother Res. 2008;22:91–6.CrossRefPubMedGoogle Scholar
  21. Smith C. The effects of Sceletium tortuosum in an in vivo model of psychological stress. J Ethnopharmacol. 2011;133:31–6.CrossRefPubMedGoogle Scholar
  22. Viola H, Wolfman C, Levi de Stein M, Wasowski C, Peña C, Medina JH, Paladini AC. Isolation of pharmacologically active benzodiazepine receptor ligands from Tilia tomentosa (Tiliaceae). J Ethnopharmacol. 1994;44:47–53.CrossRefPubMedGoogle Scholar
  23. Viola H, Wasowski C, Marder M, Wolfman C, Paladini AC, Medina JH. Sedative and hypnotic properties of Salvia guaranitica St. Hil. and of its active principle, Cirsiliol. Phytomedicine. 1997;4:47–52.CrossRefPubMedGoogle Scholar
  24. Wei W, Guo WY. Study on ultrasonic-surfactant extraction of Total flavonoids from Albizia julibrissin flower by response surface methodology. Zhong Yao Cai. 2015;38:606–9.PubMedGoogle Scholar

Copyright information

© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  • Amritpal Singh Saroya
    • 1
  • Jaswinder Singh
    • 2
  1. 1.Herbal ConsultantMohaliIndia
  2. 2.Department of PharmacologySri Guru Ram Das Institute of Medical ScienceAmritsarIndia

Personalised recommendations