Mucositis: Prevention and Management
- 552 Downloads
Mucositis is defined as inflammation of mucosa as a result of damage to the mucosal lining. Oral erythema, ulceration, and pain are the chief characteristics. It is one of the commonest side effects of radiotherapy (RT) and/or chemotherapy (CT) and is also seen in patients receiving bone marrow transplantation. The severity and duration may vary from patient to patient and may depend on the type and dose of cancer therapeutic agents used .
Patient with stage 1 V carcinoma of the supraglottis on chemoradiotherapy, 5th week showing grade III mucositis (confluent ulcerations or pseudomembranes; bleeding with minor trauma, severe pain; interfering with oral intake; note the feeding tube) (MP4 56272 kb)
- 5.Elting LS, Keefe DM, Sonis ST, et al. Patient-reported measurements of oral mucositis in head and neck cancer patients treated with radiotherapy with or without chemotherapy: demonstration of increased frequency, severity, resistance to palliation and impact on quality of life. Cancer. 2008;113:2704–13.CrossRefGoogle Scholar
- 13.US Department of Health and Human Services. Common terminology criteria for adverse events (CTCAE) version 4.0. National Institutes of Health, National Cancer Institute. 2009.Google Scholar
- 23.Clarkson JE, Worthington HV, Eden OB. Interventions for treating oral mucositis for patients with cancer receiving treatment. Cochrane Database Syst Rev. 2007;1:2.Google Scholar