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Ocular Tumor and Retinal Detachment

  • Jinqiong Zhou
  • Nan Zhou
  • Wenbin Wei
Chapter

Abstract

Optic disc melanocytoma is a rare, benign, dark brown- to black-colored tumor that usually occurs on or adjacent to the optic nerve head. Papillary capillary hemangioma is one possible manifestation of ocular capillary hemangioma and may occur sporadically or as a single or first manifestation of von Hippel-Lindau disease. Retinal hemangioma includes three kinds of diseases: retinal capillary hemangioma, retinal cavernous hemangioma, and retinal plexiform hemangioma. Retinoblastoma is the most common malignant tumor in eyes of infants. Choroidal hemangioma is a benign, relatively rare hamartomatous tumor. Choroidal melanoma is the most common primary malignant tumor in adults. Uveal tumors primarily which occur in the iris can also involve the ciliary body, such as iris melanoma, iris neurofibroma, iris nerve sheath tumor, iris cyst, etc. Choroidal melanoma can also involve the ciliary body. Metastatic carcinoma to the choroid is common, with the breast and the lung as frequent primary sites; secondary exudative retinal detachment could occur in the surface of the tumor.

References

  1. 1.
    Thanos A, Gilbert AL, Gragoudas ES. Severe vision loss with optic disc neovascularization after hemiretinal vascular obstruction associated with optic disc melanocytoma. JAMA Ophthalmol. 2015;133(10):e151502.CrossRefGoogle Scholar
  2. 2.
    Salvanos P, Utheim TP, MC M, Eide N, Bragadόttir R. Autofluorescence imaging in the differential diagnosis of optic disc melanocytoma. Acta Ophthalmol. 2015;93(5):476–80.CrossRefGoogle Scholar
  3. 3.
    Shields JA, Demirci H, Mashayekhi A, Eagle RC Jr, Shields CL. Melanocytoma of the optic disk: a review. Surv Ophthalmol. 2006;51:93–104.CrossRefGoogle Scholar
  4. 4.
    Krohn J, Kjersem B. Stereo fundus photography in the diagnosis of optic disc melanocytoma. Acta Ophthalmol. 2011;89:e533–4.CrossRefGoogle Scholar
  5. 5.
    Schmidt-Erfurth UM, Kusserow C, Barbazetto IA, Laqua H. Benefits and complications of photodynamic therapy of papillary capillary hemangiomas. Ophthalmology. 2002;109(7):1256–66.CrossRefGoogle Scholar
  6. 6.
    Kim HM, Park KH, Woo SJ. Massive exudative retinal detachment following photodynamic therapy and intravitreal bevacizumab injection in retinal capillary hemangioma. Korean J Ophthalmol. 2015;29(2):143–5.CrossRefGoogle Scholar
  7. 7.
    Palioura S, Gobin YP, Brodie SE, Marr BP, Dunkel IJ, Abramson DH. Ophthalmic artery chemosurgery for the management of retinoblastoma in eyes with extensive (>50%) retinal detachment. Pediatr Blood Cancer. 2012;59(5):859–64.CrossRefGoogle Scholar
  8. 8.
    Ong SJ, Chao AN, Wong HF, Liou KL, Kao LY. Selective ophthalmic arterial injection of melphalan for intraocular retinoblastoma: a 4-year review. Jpn J Ophthalmol. 2015;59(2):109–17.CrossRefGoogle Scholar
  9. 9.
    Lindner T, Langner S, Falke K, Walter U, Krüger PC, Pohlmann A, Zimpfer A, Stahnke T, Hadlich S, Guthoff R, Erbersdobler A, Niendorf T, Stachs O. Anatomic and pathological characterization of choroidal melanoma using multimodal imaging: what is practical, what is needed? Melanoma Res. 2015;25(3):252–8.CrossRefGoogle Scholar
  10. 10.
    Anaya-Pava EJ, Saenz-Bocanegra CH, Flores-Trejo A, Castro-Santana NA. Diffuse choroidal hemangioma associated with exudative retinal detachment in a Sturge-Weber syndrome case: photodynamic therapy and intravitreous bevacizumab. Photodiagnosis Photodyn Ther. 2015;12(1):136–9.CrossRefGoogle Scholar
  11. 11.
    Boixadera A, García-Arumí J, Martínez-Castillo V, Encinas JL, Elizalde J, Blanco-Mateos G, Caminal J, Capeans C, Armada F, Navea A, Olea JL. Prospective clinical trial evaluating the efficacy of photodynamic therapy for symptomatic circumscribed choroidal hemangioma. Ophthalmology. 2009;116(1):100–5.CrossRefGoogle Scholar
  12. 12.
    Nugent R, Lee L, Kwan A. Photodynamic therapy for diffuse choroidal hemangioma in a child with Sturge-Weber syndrome. J AAPOS. 2015;19(2):181–3.CrossRefGoogle Scholar
  13. 13.
    Shields CL, Shields JA, Gross NE, Schwartz GP, Lally SE. Survey of 520 eyes with uveal metastases. Ophthalmology. 1997;104:1265–76.CrossRefGoogle Scholar
  14. 14.
    Freedman MI, Folk JC. Metastatic tumors to the eye and orbit. Patient survival and clinical characteristics. Arch Ophthalmol. 1987;105:1215–9.CrossRefGoogle Scholar
  15. 15.
    Inoue K, Numaga J, Kaji Y, Toda J, Kato S, Sakurai M, Ikeda M, Motoi N, Murakami T, Fujino Y. Bilateral choroidal metastases secondary to uterocervical carcinoma of the squamous cell type. Am J Ophthalmol. 2000;130(5):682–4.CrossRefGoogle Scholar
  16. 16.
    Kubota-Taniai M, Oshitari T, Handa M, Baba T, Yotsukura J, Yamamoto S. Long-term success of intravitreal bevacizumab for choroidal neovascularization associated with choroidal osteoma. Clin Ophthalmol. 2011;5:1051–5.CrossRefGoogle Scholar

Copyright information

© Springer Nature Singapore Pte Ltd. and Beijing Science and Technology Press 2018

Authors and Affiliations

  • Jinqiong Zhou
    • 1
  • Nan Zhou
    • 1
  • Wenbin Wei
    • 1
  1. 1.Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical UniversityBeijingChina

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