Probiotic Biosurfactants: A Potential Therapeutic Exercises in Biomedical Sciences

  • Priyanka Saha
  • Deepa Nath
  • Manabendra Dutta Choudhury
  • Anupam Das TalukdarEmail author


Biosurfactant is the exudates of microbial metabolism and also familiar as surface-active compounds. It has netted its rank in both industrial and environmental portion but in medical science, use of same is still in nascent stage. Important probiotics like lactic acid bacteria, Bacillus spp. make up the vital constituents of human microflora, possesses an enormous antimicrobial, antibiofilm, antitumor and anti-adhesive potential. Structural novelty and diverse properties make biosurfactant as probable candidates for beneficial applications today. To attain anticipated success under this approach it is vital to keep in mind that certain microbes must transport some antimicrobial and surface activity. Surface activity aids in potential association with cell membranes of different organisms. Evident from the published literature that microbial surfactants such as lipopeptide and glycolipid showed to inhibit the transmission of cancerous cells and following apoptosis by rapid cell rupture. In drug discovery, biosurfactants appear with a promising drug delivery mode. In general, biosurfactants have strong bactericidal and fungicidal properties. Anti-adhesiveness of biosurfactant against pathogenic candidates marks them helpful for curing many diseases and also as therapeutic candidates. Structural diversity, their mode of actions and future prospects in medical sciences are the points of discussions under this review.


Biosurfactants Probiotic Biomedical Antimicrobial Lipopeptide Glycolipid 


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Copyright information

© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  • Priyanka Saha
    • 1
  • Deepa Nath
    • 2
  • Manabendra Dutta Choudhury
    • 1
  • Anupam Das Talukdar
    • 1
    Email author
  1. 1.Department of Life Science & BioinformaticsAssam UniversitySilcharIndia
  2. 2.Department of Botany and BiotechnologyKarimganj CollegeKarimganjIndia

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