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Phototoxicity of Hair Dyes: Challenge for Tropical Countries

  • Shruti Goyal
  • Ajeet Kumar Srivastav
  • Saroj K. Amar
  • Shikha Agnihotry
  • Ratan Singh Ray
Chapter

Abstract

In current scenario, utilization of hair dyes and personal care products (PCPs) has been increasing globally day to day. The US Aliment, Dye and Cosmetic Act require prior approbation of color additives, dyes, and cosmetics afore relinquishing product in market, but in India there was no guideline yet. According to survey more than one-third of women over age 18 and about 10% of men over age 40 utilize some type of hair dye coloring products for better physical appearance. Mostly, hair dye ingredient forms photoproduct after exposure of UV irradiation due to the presence of benzene nucleus or bulky structure with strong functional group. Photocytotoxicity results of hair dye ingredients in human keratinocyte cells illustrated the paramount reduction in cell survival. Photogenotoxic potential of hair dye was also reported in various past studies. Thus, study focused on hair dye which induced photogenotoxicity, photocytotoxicity, and apoptotic cell death through disturbing normal cell physiology. Therefore, joint exposure of sunlight and long-term use of hair dyes enhance oxidative stress in human skin which may lead to various skin diseases in human beings including mutation and various types of skin cancer.

Keywords

Phototoxicity Hair dyes PCPs UV-R Sunlight 

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Copyright information

© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  • Shruti Goyal
    • 1
  • Ajeet Kumar Srivastav
    • 1
    • 2
  • Saroj K. Amar
    • 3
  • Shikha Agnihotry
    • 4
  • Ratan Singh Ray
    • 1
  1. 1.Photobiology Laboratory, System Toxicology and Health Risk Assessment GroupCSIR-Indian Institute of Toxicology ResearchLucknowIndia
  2. 2.Babu Banarasi Das UniversityLucknowIndia
  3. 3.Department of Forensic Science, School of Bioengineering and BiosciencesLovely Professional UniversityPhagwaraIndia
  4. 4.Department of Biomedical-informaticsSanjay Gandhi Post Graduate InstituteLucknowIndia

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