Advertisement

Epilepsy

  • J. B. Sharma
  • Monica Gupta
Chapter

Abstract

Epilepsy in pregnancy presents unique challenges to the clinician. Less than 1% of pregnant women experience seizure attack during pregnancy. Prompt management of these women in a timely fashion is essential to prevent fatal maternal and foetal complications. Pre-pregnancy counselling and dose adjustment of anti-epileptic drugs to maintain 9–12 month seizure-free period prior to pregnancy ensure minimal risk of seizure recurrence during pregnancy. This chapter mainly focuses on acute management of pregnant women presenting with seizure and status epilepticus during pregnancy.

References

  1. 1.
    Edey S, Moran N, Nashef L. SUDEP and epilepsy-related mortality in pregnancy. Epilepsia. 2014;55:e72–4.CrossRefGoogle Scholar
  2. 2.
    Krumholz A, Wiebe S, Gronseth G, et al. Practice parameter: evaluating an apparent unprovoked first seizure in adults (an evidence-based review): report of the quality standards sub- committee of the American Academy of Neurology and the American Epilepsy Society. Neurology. 2007;69(21):1996–2007.CrossRefGoogle Scholar
  3. 3.
    Practice ACoO. ACOG Committee Opinion. Number 299, September 2004 (replaces No.158, September 1995). Guidelines for diagnostic imaging during pregnancy. Obstet Gynecol. 2004;104(3):647–51.CrossRefGoogle Scholar
  4. 4.
    Proposal for revised clinical and electroencephalographic classification of epileptic seizures. From the commission on classification and terminology of the international league against epilepsy. Epilepsia. 1981;22(4):489–501.Google Scholar
  5. 5.
    Harden CL, Hopp J, Ting TY, et al. Practice parameter update: management issues for women with epilepsy-focus on pregnancy (an evidence-based review): obstetrical complications and change in seizure frequency. Neurology. 2009;73:126–32.CrossRefGoogle Scholar
  6. 6.
    Thomas SV, Syam U, Devi SJ. Predictors of seizures during pregnancy in women with epilepsy. Epilepsia. 2012;53(5):e85–8.CrossRefGoogle Scholar
  7. 7.
    Abe K, Hamada H, Yamada T, Obato-Yasuoka M, Minakami H, Yoshikawa H. Impact of planning of pregnancy in women with epilepsy on seizure control during pregnancy and on maternal and neonatal outcomes. Seizure. 2014;23:112–6.CrossRefGoogle Scholar
  8. 8.
    Cunnington MC, Weil JG, Messenheimer JA, et al. Final results from 18 years of the international lamotrigine pregnancy registry. Neurology. 2011;76:1817–23.CrossRefGoogle Scholar
  9. 9.
    EURAP Study Group. Seizure control and treatment in pregnancy: observations from the EURAP 1129 epilepsy pregnancy registry. Neurology. 2006;66:354–60.CrossRefGoogle Scholar
  10. 10.
    Alldredge BK, Gelb AM, Isaacs SM, Corry MD, Allen F, Ulrich S, et al. A comparison of lorazepam, 1134 diazepam, and placebo for the treatment of out-of-hospital status epilepticus. N Engl J Med. 2001;345:631–7.CrossRefGoogle Scholar

Copyright information

© Springer Nature Singapore Pte Ltd. 2020

Authors and Affiliations

  • J. B. Sharma
    • 1
  • Monica Gupta
    • 1
  1. 1.Department of Obstetrics & GynaecologyAll India Institute of Medical SciencesNew DelhiIndia

Personalised recommendations