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Imaging: US and CT

  • Hisato Igarashi
  • Testuhide Ito
  • Kosei Ishigami
  • Masayuki Hijioka
  • Hirotaka Ohara
Chapter

Abstract

IgG4-related disease (IgG4-RD) is characterized by increased serum levels of IgG4, a lymphoplasmacytic infiltrate composed of IgG4-positive plasma cells, storiform fibrosis, obliterative phlebitis, and mild to moderate eosinophilia [1]. IgG4-related sclerosing cholangitis (IgG4-SC) is a biliary lesion associated with IgG4-RD, which is frequently seen in elderly men, characterized by obstructive jaundice owing to a bile duct stricture and responds well to steroid therapy [2]. Recently, the first clinical diagnostic criteria for IgG4-SC were proposed in Japan [3]. As in the diagnostic items of the 2012 IgG4-SC diagnostic criteria, biliary tract imaging of IgG4-SC reveals diffuse or segmental narrowing of the intrahepatic and/or extrahepatic bile duct associated with thickening of the bile duct wall [3].

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Copyright information

© Springer Science+Business Media Singapore 2019

Authors and Affiliations

  • Hisato Igarashi
    • 1
  • Testuhide Ito
    • 2
  • Kosei Ishigami
    • 3
  • Masayuki Hijioka
    • 2
  • Hirotaka Ohara
    • 4
  1. 1.Igarashi Medical ClinicFukuokaJapan
  2. 2.Neuroendocrine Tumor Centre, Fukuoka Sanno HospitalInternational University of Health and WelfareFukuokaJapan
  3. 3.Department of Clinical Radiology, Graduate School of Medical SciencesKyushu UniversityFukuokaJapan
  4. 4.Department of Community-Based Medical EducationNagoya City University Graduate School of Medical SciencesNagoyaJapan

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