Mimosa tenuiflora (Willd.) Poir.

  • Andrêsa Suana Argemiro Alves
  • Gilney Charll Santos
  • Ulysses Paulino Albuquerque
Part of the Medicinal and Aromatic Plants of the World book series (MAPW, volume 5)


The use of Mimosa tenuiflora ([Willd.] Poir.) dates back to pre-colonial American civilizations. This plant has been used for a variety of purposes, such as magic-religious rituals; as a medicinal resource with anti-inflammatory, antimicrobial and cicatrization properties; for fence construction and as a fuel. It contains high concentrations of tannins and flavonoids, which are mainly used to treat skin diseases. M. tenuiflora also contains N,N-dimethyltryptamine, a tryptamine alkaloid with psychoactive properties, which causes changes in humans’ mental states. Therefore, most of the studies on the bioactive compounds of M. tenuiflora have focused on its psychoactive actions and on the effectiveness of the flavonoids and tannins for cicatrization.


Skin tree Fabaceae Jurema Psychotropic plants Tepezcohuite 



We are especially grateful to the National Institute of Science and Technology in Ethnobiology, Bioprospecting and Nature Conservation, certified by CNPq, with financial support from FACEPE (Foundation for the Support of Science and Technology of the State of Pernambuco).


  1. Agra MF, Baracho GS, Nurit K, Basílio IJLD, Coelho VPM (2007) Medicinal and poisonous diversity of the flora of “Cariri Paraibano”, Brazil. J Pharmacogz 111:383–395Google Scholar
  2. Albuquerque UP, Andrade LHC. As plantas na medicina e na magia dos cultos afro-brasileiros. Tópicos em Conservação, Etnobotânica e Etnofarmacologia de Plantas Medicinais (Albuquerque UP, Almeida CFCBR, Andrade JFM). NUPEEA, Recife, 51–76, 2005Google Scholar
  3. Albuquerque UP, Medeiros PM, Almeida ALS, Monteiro JM, Lins Neto EMF, Melo JG, Santos JP (2007) Medicinal plants of the caatinga (semi-arid) vegetation of NE Brazil: a quantitative approach. J Ethnopharmacol 114:325–354CrossRefGoogle Scholar
  4. Almeida CFCBR, e Silva Lima TC, ELC A, MBS M, Albuquerque UP (2005) Life strategy and chemical composition as predictors of the selection of medicinal plants from the caatinga (Northeast Brazil). J Arid Environ 62:127–142CrossRefGoogle Scholar
  5. Anton R, Jiang Y, Weniger B, Beck JP, Rivier L (1993) Pharmacognosy of Mimosa tenuiflora (Willd.) Poiret. J Ethnopharmacol 38:153–157CrossRefGoogle Scholar
  6. Banerji R, Prakash D, Misra G, Nigam SK (1981) Cardiovascular and hemolytic activity of Saponins. Indians Drugs 52:121–124Google Scholar
  7. Barneby CR (1991) Sensitivae censitae. The genus Mimosa L. (Mimosoideae) in the new world. N Y Bot Gard 65:1–835Google Scholar
  8. Bautista E, Calzada F, Ortega A, Yépez-Mulia L (2011) Antiprotozoal activity of flavonoids isolated from Mimosa tenuiflora (Fabaceae-Mimosoideae). J Mex Chem Soc 55(4):251–253Google Scholar
  9. Bezerra DAC, Rodrigues FFG, Costa JGM, Pereira AV, Sousa EO, Rodrigues OG (2011) Abordagem fitoquímica, composição bromatológica e atividade antibacteriana de Mimosa tenuiflora (Willd.) Poiret e Piptadenia stipulacea (Benth.) Ducke. Acta Sci Biol Sci.
  10. Bitencourt MAO, Lima MCJS, Torres-Rêgo M, Fernandes JM, Silva-Júnior AA, Tambourgi DV, Zucolotto SM, Fernandes-Pedrosa MF (2014) Neutralizing effects of Mimosa tenuiflora extracts against inflammation caused by Titus serrulatus scorpion venom. BioMed Res Int, ID 378235, 8 pages CrossRefGoogle Scholar
  11. Brierley DI, Davidson C (2012) Developments in harmine pharmacology—implications for ayahuasca use and drug-dependence treatment. Prog Neuro-Psychopharmacol Biol Psychiatry 39:263–272CrossRefGoogle Scholar
  12. Cadena-Iñiguez P, Cruz-Morales FDC, Ballinas-Albores E (2014) Tepezcohuite (Mimosa tenuiflora (L.) Willd) el árbol de la piel. Agroproductividad 7:10–16Google Scholar
  13. Camargo-Ricalde SL (2000) Descripción, distribuición, anatomía, composición química y usos de Mimosa tenuiflora (Fabaceae-Mimosoideae) en México. Rev Biol Trop 48(4):939–954PubMedGoogle Scholar
  14. Camargo-Ricalde SL, García-García V (2001) El género Mimosa L. (Fabaceae) y la restauración ecológica. Contactos 39:34–42Google Scholar
  15. Camargo-Ricalde SL, Grether R (1998) Germinación, dispersión y estabelecimiento de plântulas de Mimosa tenuiflora (Leguminosae) em México. Rev Biol Trop 46(3):543–554Google Scholar
  16. Cartaxo SL, Souza MMA, Albuquerque UP (2010) Medicinal plants with bioprospecting potential used in semi-arid northestearn Brazil. J Ethnopharmacol 131:326–342CrossRefGoogle Scholar
  17. Diesel KMF, Costa FSL, Pimenta AS, Lima KMG (2014) Near-infrared spectroscopy and wavelength selection for estimating basic density in Mimosa tenuiflora [Willd.] Poiret wood. Wood Sci Technol 48:949–959CrossRefGoogle Scholar
  18. Dourado DAO, Conceição AS, Santos-Silva J (2013) O gênero Mimosa L. (Leguminosae: Mimosoideae) na APA Serra Branca/Raso da Catarina, Bahia, Brasil. Biota Neotrop 13(4):225–240CrossRefGoogle Scholar
  19. Figueirôa JM, Pareyn FGC, Araújo EL, Silva CE, Santos VF, Cutler DF, Baracat A, Gasson P (2006) Effects of cutting regimes in the dry and wet season on survival and sprouting of woody species from the semi-arid caatinga of northeast Brazil. Forest Ecol Manag 229:294–303CrossRefGoogle Scholar
  20. Gardner D, Riet-Correa F, Lemos D, Welch K, Pfister J, Panter K (2014) Teratogenic effects of Mimosa tenuiflora in a rat model and possible role of N-Methyl- and N,N-Dimethyltryptamine. J Agric Food Chem 62:7398–7401CrossRefGoogle Scholar
  21. Gaujac A, Martinez ST, Gomes AA, Andrade SJ, Pinto AC, David JM, Navickiene S, Andrade JB (2013) Application of analytical methods for the structural characterization and purity assessment of N,N-dimethyltrhryptamine, a potent psychedelic agent isolated from Mimosa tenuiflora inner barks. Microchem J 109:78–83CrossRefGoogle Scholar
  22. Heinrich M, Kuhnt M, Wright CW, Rimpler H, Phillipson JD, Schandelmaier A, Parasitological WDC (1992) Microbiological evaluation of Mixe Indian medicinal plants (Mexico). J Ethnopharmacol 36:81–85CrossRefGoogle Scholar
  23. Jiang Y, Massiot G, Lavaud C, Teulon J, Guéchot C, Haag-Berrurier M, Anton R (1991) Triterpenoid glycosides from the bark of Mimosa tenuiflora. Phytochemistry 30:2357–2360CrossRefGoogle Scholar
  24. Jiang YL, Weniger B, Haag-Berrurier M, Anton R, Beck JP, Italiano L (1992) Effects of saponins from Mimosa tenuiflora on lymphoma cells and lymphocytes. Phytoter Res 6:310–313CrossRefGoogle Scholar
  25. Lammoglia-Ordiales L, Vega-Memije ME, Herrera-Arellano A, Rivera-Arce E, Agüero J, Vargas-Martinez F, Contreras-Ruiz J (2012) A randomised comparative trial on the use of a hydrogel with tepescohuite extract (Mimosa tenuiflora cortex extract-2G) in the treatment of venous leg ulcers. Int Wound J 9(4):412–441CrossRefGoogle Scholar
  26. Lewis GP, Schrire B, MacKinder B, Lock M (2005) Legumes of the world. Royal Botanical Gardens, KewGoogle Scholar
  27. Lucena RFP, Abreu DBO, Leal JLM, Guerra NM, Leite AP, Ribeiro JES, Ribeiro JPO, Nunes EN, Anselmo MGV, Alves CAB, Sousa Júnior SP, Nunes AT, Souto JS, Carvalho TKN, Sousa RF (2014) Traditional knowledge and use of Mimosa tenuiflora (Wild.) Poir. (jurema-preta) in the semi-arid region from Northeastern Brazil. Gaia Scientia 8(1):34–50Google Scholar
  28. Martel-Estrada SA, Rodríguez-Espinoza BR, Santos-Rodrígues E, Jiménez-Vega F, García-Cassillas PE, Martinéz-Pérez CA, Armendáriz IO (2015) Biocompatibility of chitosan/Mimosa tenuiflora scaffolds for tissue engineering. J Alloy Comp 643(1):S119–S123CrossRefGoogle Scholar
  29. Mattos PP, Braz EM, Domene VD, Sampaio EVSB, Gasson P, Payren FGC, Alvarez IA, Baracat A, Araújo EL (2015) Climate-tree growth relationships of Mimosa tenuiflora in seasonally dry tropical forest, Brazil. Cerne 21:141–149. CrossRefGoogle Scholar
  30. Meckes-Lozoya M, Lozoya X, Marles R, Soucy-Breau C, Avalokitesvarasen AJ (1990a) N,N-dimethyltryptamine alkaloid in Mimosa tenuiflora bark (Tepescohuite). Arch Invest Med 21:175–177Google Scholar
  31. Meckes-Lozoya M, Lozoya X, Gonzalez J (1990b) Propiedades farmacológicas in vitro de algunos extractos de Mimosa tenuiflora (tepescohuite). Arch Invest Med 21:163–169Google Scholar
  32. Mota CN, Albuquerque UP (2006) As muitas faces da jurema: de espécies botânica à divindade afro-indígena, 2ª edn. NUPEEA, RecifeGoogle Scholar
  33. Mucci M, Sciocchetti M, Benvenuti C (2006) Clinical efficacy and safety of Mimosa tenuiflora bark extract in the rhagades of the nipple. G Ital Ostetricia Ginecol 23(3):106–114Google Scholar
  34. Muelas-Serrano S, Nogal JJ, Martinéz-Díaz RA, Escario JA, Martínez-Fernández AR, Gómez-Barrio A (2000) In vitro screening of American plant extracts on Trypanosoma cruzi and Trichomonas vaginalis. J Ethnopharmacol 71:101–107CrossRefGoogle Scholar
  35. Nascimento VT, Sousa LG, Alves AGC, Araújo EL, Albuquerque UP (2009) Rural fences in agricultural landscapes and their conservation role in an area of caatinga (dryland vegetation) in Northeast Brazil. Environ Dev Sustain 11:1005–1029CrossRefGoogle Scholar
  36. Padilha IQM, Pereira AV, Rodrigues OG, Siqueira-Júnior JP, Pereira MS (2010) Antimicrobial activity of Mimosa tenuiflora (Willd.) Poir. From northeast Brazil against clinical isolates of Staphylococcus aureus. Rev Bras Farmacog 20(1):45–47CrossRefGoogle Scholar
  37. Rivera-Arce E, Chávez-Soto MA, Herrera-Arellano A, Arzate S, Agüero J, Feria-Romero IA, Cruz-Guzmán A, Lozoya X (2007a) Therapeutic effectiveness of a Mimosa tenuiflora cortex extract in venous leg ulceration treatment. J Ethnopharmacol 109:523–528CrossRefGoogle Scholar
  38. Rivera-Arce E, Gattuso M, Alvarado R, Zárate E, Agüero J, Feria I, Loyoza X (2007b) Pharmacognostical studies of the plant drug Mimosa tenuiflorae cortex. J Ethnopharmacol 113:400–408CrossRefGoogle Scholar
  39. Rodrigues MG, Campos RBC (2013) Caminhos da visibilidade: a ascensão do culto a jurema no campo religioso do Recife. Afro-Ásia 47:269–291CrossRefGoogle Scholar
  40. Santos EA, Carvalho CM, Costa ALS, Conceição AS, Moura FBP, Santana AEG (2012) Bioactivity evaluation of plant extracts used in indigenous medicine against the snail, Biomphalaria glabrata, and the larvae of Aedes aegypti. Evid Based Complement Altern Med. Google Scholar
  41. Santos-Silva J, Sales MF (2010) Diversidade e potencial econômico de Mimosa L. (Leguminosae-Mimosoideae) em Pernambuco, Brasil. In: Albuquerque UP, Moura AN, Araújo EL (eds) Biodiversidade, potencial econômico e processos ecofisiológicos em ecossistemas nordestinos. NUPEEA, Recife, pp 283–313Google Scholar
  42. Shrivastava R (2011) Clinical evidence to demonstrate that simultaneous growth of epithelial and fibroblast cells is essencial to deep wound healinhg. Diabetes Res Clin Pr 92:92–99CrossRefGoogle Scholar
  43. Silva VA, Gonçalves GF, Pereira MSV, Gomes IF, Freitas AFR, Diniz MFFM, Pêssoa HLF (2013) Assessment of mutagenic, antimutagenic and genotoxicity effects of Mimosa tenuiflora. Rev Bras Farmacog 23(2):329–334CrossRefGoogle Scholar
  44. Simon MF, Grether R, Queiroz LP, Särkinen TE, Dutra VF, Hughes CE (2011) The evolutionary history of Mimosa (Leguminosae): toward a phylogeny of the sensitive plants. Am J Bot 98(7):1201–1221CrossRefGoogle Scholar
  45. Siqueira CFQ, Cabral DLV, Sobrinho TJSP, Amorim ELC, Melo JG, Araújo TAS, Albuquerque UP (2012) Levels of tannins and flavonoids in medicinal plants: evaluating bioprospecting strategies. Evid Based Complement Altern Med. CrossRefGoogle Scholar
  46. Souza RSO, Albuquerque UP, Monteiro JM, Amorim ELC (2008) Jurema-preta (Mimosa tenuiflora [Willd.] Poir.): a review of its tradicional use, phytochemistry and pharmacology. Braz Arch Biol Technol 51(5):937–947CrossRefGoogle Scholar
  47. Tellez PJ, Dupoy de Guitard J (1990) Pharmaceutical preparation containing Mimosa tenuiflora extract with skin-regenerating properties. Patent Eur Pat Appl 349:469Google Scholar
  48. Vilarreal ML, Alonso D, Melesio G (1992) Cytotoxic activity of Mexican plants used in traditional medicine. Fitoterapia 43:518–521Google Scholar
  49. Zippel J, Deters A, Hensel A (2009) Arabinogalactans from Mimosa tenuiflora (Willd.) Poiret bark as active principles for wound-healing properties: specific enhancement of dermal fibroblast activity and minor influence on HaCaT keratinocytes. J Ethnopharmacol 124:391–396CrossRefGoogle Scholar

Copyright information

© Springer Nature B.V. 2018

Authors and Affiliations

  • Andrêsa Suana Argemiro Alves
    • 1
  • Gilney Charll Santos
    • 1
  • Ulysses Paulino Albuquerque
    • 2
  1. 1.Laboratório de Ecologia e Evolução de Sistemas Socioecológicos, Departamento de BotânicaUniversidade Federal de PernambucoRecifeBrazil
  2. 2.Departamento de Botânica, Centro de BiociênciasUniversidade Federal de PernambucoRecifeBrazil

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