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H-1 Antigenicity of Rat Tumours after In Vivo Passage and In Vitro Cultivation

  • Drahomira Křenová
  • V. Křen
  • O. Štark
Chapter

Summary

Tumour host compatibility of H-1 alleles was found to be most important for tumour growth, indicating the predominant role of the H-1 system in the rat strains tested. The explanted tumour cells preserved their H-1 antigenicity during long term cultivation in vitro as proved by immunization and absorption techniques.

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References

  1. Frenzl, B., Brdička, R., Křen, V. and Štark, O., 1965. Erythrocyte B1 antigen in inbred rat strains. In: Blood groups of animals, Prague, p. 197.CrossRefGoogle Scholar
  2. Křen, V., Braun, A. and Křenová, D., 1968. Transplantability of tumour induced in rats by Ferri- dextran Spofa, Neoplasma, 15, 29–38.PubMedGoogle Scholar
  3. Křenová, D., Křen, V., and Štark, O., 1968. Properties of the rat tumour FEDEX-WP during long-term cultivation in vitro, Neoplasma (In press).Google Scholar
  4. Palm, J., 1962. Current status of blood groups in rats, Ann. N.Y. Acad. Sci., 97, 57–68.PubMedCrossRefGoogle Scholar
  5. Štark, O., Křen, V., Frenzl, B., and Brdička, R., 1968. The main histocompatibility system of the rat. In: Advance in transplantation, Copenhagen, p. 331.Google Scholar

Copyright information

© Springer Science+Business Media Dordrecht 1970

Authors and Affiliations

  • Drahomira Křenová
    • 1
  • V. Křen
    • 1
  • O. Štark
    • 1
  1. 1.Faculty of General Medicine, Department of General BiologyCharles UniversityPragueCzechoslovakia

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