Ontogenic and Familial Variation in Serum Alkaline Phosphatase of Pigs
Qualitative and quantitative variation in pig serum alkaline phosphatase activity is demonstrated. Polymorphic-type patterns of alkaline phosphatase activity are detectable at 1 to 3 weeks of age by starch gel electrophoresis. The patterns seen are due to a variable fast component, which disappears after 3 weeks of age, and appears to be a feature of normal development. Alkaline phosphatase in pre-colostral serum samples exhibits a different electrophoretic mobility to that shown by samples taken after 4 days of age. The change in mobility is not related to colostrum uptake. Quantitative estimations of alkaline phosphatase activity in serum appears to be highest in pre-colostral samples, then rapidly decreases over a period of 4 weeks, and subsequently decreases gradually. In studies of serum alkaline phosphatase levels taken at weekly intervals from seventeen litters for a period of 9 weeks significant differences between litters can be detected.
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