The Ontogenetic Development of H-2 Antigens in Vivo and in Vitro

  • J. Klein


At the present time, three blood group systems are known in mice: The systems H-2 (Gorer 1936) and the system H-5 and H-6 (Amos et al. 1963). In addition to erythrocytes and leucocytes, the antigens of the H-2 system are also present in the cells of other tissues such as the liver and spleen and represent strong transplantation antigens. The mouse belongs to the animals most frequently used for the study of transplantation problems and therefore it seemed useful to us to accumulate a body of information about H-2 antigens.


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Copyright information

© Springer Science+Business Media Dordrecht 1965

Authors and Affiliations

  • J. Klein
    • 1
  1. 1.Institute of Experimental Biology and GeneticsCzechoslovak Academy of SciencesPragueCzech Republic

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