Studies on Protein Polymorphism in Pigs, Horses and Cattle

  • M. A. Graetzer
  • M. Hesselholt
  • J. Moustgaard
  • M. Thymann


By means of starch gel electrophoresis and benzidine stain of pig sera, to which haemoglobin was added prior to electrophoresis, 10 protein components were observed. According to convention the components were designated Hp 1—Hp 10. Grouped variations involving Hp 1, Hp 2 and Hp 3 in the individual sera were observed. Family investigations supported the hypothesis that the polymorphism exhibited was under simple genetic control and determined by 3 allelic genes (Kristjansson, 1961). During later Danish investigations a new component Hp 0 was found. Family investigations comprising pigs of Danish Landrace have supported the hypothesis that the synthesis of Hp 0, Hp 1, Hp 2 and Hp 3 is determined by 4 alleles: Hp0, Hp1, Hp2, and Hp3 with codominant mode of inheritance (Brummerstedt-Hansen et al. 1962 a, b; Hesselholt 1963a, b).


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  1. Aschaffenburg, R. (1963). J. Dairy Res. 30: 251.CrossRefGoogle Scholar
  2. Aschaffenburg, R. (1964). Nature 192: 431.CrossRefGoogle Scholar
  3. Ashton, G. C. (1958). Nature 182: 1029.PubMedCrossRefGoogle Scholar
  4. Broman, L. (1958). Nature 182: 1655.PubMedCrossRefGoogle Scholar
  5. Brummerstedt-Hansen, E., M. Hesselholt, B. Larsen, J. Moustgaard, I. Moller, P. B. Nielsen and B. Palludan (1962a). The 8th Anim. Blood Group Conf. in Europe, Ljubljana, Yugoslavia.Google Scholar
  6. Brummerstedt-Hansen, E. and M. Hesselholt (1962b). Annual Report, The Royal Veterin. and Agric. Coll., Inst. f. Sterility Research 211. Braend, M. and C. Stormont (1964).Google Scholar
  7. Nord. Vet.-Med. 16: 31. Braend, M. (1964). Nord. Yet. Med. 16: 363.Google Scholar
  8. Fishman, W. H. (1960). In The Plasma Proteins 2, Chap. 12, Acad. Press, N. Y. and London.Google Scholar
  9. Hesselholt, M. (1963a). Acta Yet. Scand. 4: 238.Google Scholar
  10. Hesselholt, M. (1963b). Annual Report, The Royal Yeterin. and Agric: Coll., Inst. f. Sterility Research 93.Google Scholar
  11. Holmberg, C. C. and Laurell, C. B. (1948). Acta Chem. Scand. 2: 550.CrossRefGoogle Scholar
  12. Holmberg, C. C. and Laurell, C. B. (1951). Acta Chem. Scand. 5: 476.CrossRefGoogle Scholar
  13. Imlah, P. (1963). Personal communication.Google Scholar
  14. Kiddy, C. A., J. O. Johnston and M. P. Thompson (1964). J. Dairy Sei. 47: 147.CrossRefGoogle Scholar
  15. King, J. W. B. (1963). Personal communication.Google Scholar
  16. Kristjansson, F. K. (1961). Genetics 46: 907.PubMedGoogle Scholar
  17. McAlister, R., G. M. Martin and E. P. Benditt (1961). Nature 190: 927.PubMedCrossRefGoogle Scholar
  18. Morell, A. G. and I, H, Scheinberg (1960). Science 131: 930.PubMedCrossRefGoogle Scholar
  19. Poulik, M. D. and O. Smithies (1958). Biochem. J. 68: 636.PubMedGoogle Scholar
  20. Poulik, M. D. and A. G. Beam (1962). Clin. Chim. Acta 7: 374.PubMedCrossRefGoogle Scholar
  21. Schmid, D. O. (1962). Z. Immunitätsforsch. 124: 219.Google Scholar
  22. Sass-Kortsak, A., S. J. Jackson, and A. F. Charles (1960). Yox Sang. 5: 87.Google Scholar
  23. Thompson, M. P. (1962). Nature 195: 1001.PubMedCrossRefGoogle Scholar
  24. Thompson, M. P. (1964). Personal communication.Google Scholar
  25. Uriel, J. (1958). Nature 181: 999.PubMedCrossRefGoogle Scholar
  26. Uriel, J. (1963). Ann. N. Y. Acad. Sc. 103: 493.Google Scholar
  27. Wake, R. C. and R. L. Baldwin (1961). Biochim. et Biophys. Acta 47: 225.Google Scholar
  28. White, A., P. Handler, E. Smith and D. Stetten (1954). Principles of Biochemistry, Chap. 11, p. 260, McGraw-Hill Book Co. N. Y.Google Scholar

Copyright information

© Springer Science+Business Media Dordrecht 1965

Authors and Affiliations

  • M. A. Graetzer
    • 1
  • M. Hesselholt
    • 1
  • J. Moustgaard
    • 1
  • M. Thymann
    • 1
  1. 1.Department of Physiology, Endocrinology and Blood GroupingThe Royal Veterinary and Agricultural CollegeCopenhagenDenmark

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