Interferons: therapy for cancer

  • David Goldstein
  • Robert Jones
  • Richard V. Smalley
  • Ernest C. Borden


Isaacs and Lindemann, in England, first characterized interferon (IFN) in 1957 and coined the word to signify a protein, elaborated by virus-infected cells, that functions to prevent their infection by a second virus [107]. However, difficulties with chemical isolation and characterization led to great skepticism about the molecule’s existence; indeed, “the scientific community dubbed the discovery ‘imaginon’” [187].


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© Springer Science+Business Media Dordrecht 2003

Authors and Affiliations

  • David Goldstein
  • Robert Jones
  • Richard V. Smalley
  • Ernest C. Borden

There are no affiliations available

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