Disorders of the metabolism of larger molecules

  • M. J. Eadie
  • J. H. Tyrer


Neural tissue contains a variety of large molecules which have a number of known biological functions, as well as often providing a basis for cell structure. Proteins function both as enzymes and as receptors for the attachment of other molecules and the subsequent transduction of this attachment into further biochemical events; nucleic acids convey genetic information; carbohydrates (as glycogen) are stores of energy, and lipids appear to have structural, permeability (membrane) and insulating functions (e.g. myelin). In addition, neural tissue contains complex macromolecules formed from admixture of protein, carbohydrate and lipid components, e.g. lipoproteins, glycoproteins, glycos-aminoglycans (mucopolysaccharides) and glycolipids. Individual macro-molecules may exist in cells bonded into even larger and more complex macromolecule aggregates. For convenience, biological macromolecules are often considered in terms of their individual components which are chemically stable enough to be able to exist in isolation after preliminary separation procedures. Such components are themselves usually comparatively large molecules.


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Copyright information

© M. J. Eadie and J. H. Tyrer 1983

Authors and Affiliations

  • M. J. Eadie
    • 1
  • J. H. Tyrer
  1. 1.Department of MedicineUniversity of QueenslandBrisbaneAustralia

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