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Mental Retardation

  • Michael Egger

Abstract

The syndrome of mental retardation presents a unique challenge to the affected child or adult, to his family, and to the physician who seeks to enhance his habilitation potential. It is the most common serious disorder of childhood, and it is a major social and economic problem. Yet in our country, major interest in the mentally retarded has developed only within the last three decades. Two events, the establishment in 1950 of a citizen advocacy group called the National Association for Retarded Citizens, and President Kennedy’s 1963 federal mandate on mental retardation, were benchmarks for our nation’s modern era of care of its retarded citizens.

Keywords

Mental Retardation Marfan Syndrome Maple Syrup Urine Disease Retarded Child Spastic Cerebral Palsy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Selected Bibliography

  1. Amaurotic family idiocy. Lancet 1: 469–471 (1973).Google Scholar
  2. American Medical Association. Mental retardation. A handbook for the primary physician. JAMA 191: 183–222 (1965).Google Scholar
  3. Ampola, M. Phenylketonuria and other disorders of amino acid metabolism. Pediatr. Clin. North Am. 20: 507–536 (1973).PubMedGoogle Scholar
  4. Ando, H. Intrafamilial incidence of autism, cerebral palsy, and mongolism. J. Autism Childh. Schizophr. 5: 267–274 (1975).CrossRefGoogle Scholar
  5. Arey, J. The lipidoses. Morphologic changes in the nervous system in Gaucher’s disease, GM2 gangliosidoses and Niemann-Pick disease. Ann. Clin. Lab. Sci. 5: 475–488 (1975).PubMedGoogle Scholar
  6. Baughman, F., Higgins, J., Wadsworth, T., and Demaray, M. The carrying angle in sex chromosome anomalies. JAMA 230: 718–720 (1974).PubMedCrossRefGoogle Scholar
  7. Brinkworth, R. The unfinished child. Early treatment and training for the infant with Down’s syndrome. R. Soc. Health J. (Lond.J 95: 73–78 (1975).Google Scholar
  8. Carter, C. (ed.). Medical Aspects of Mental Retardation. Thomas, Springfield, Ill. (1965).Google Scholar
  9. Chamberlin, H. Mental subnormality. General considerations, in Pediatric Neurology. T.W. Farmer, Ed. Harper & Row, New York (1964).Google Scholar
  10. Clements, P. Variability within Down’s syndrome. Emperically observed sex differences in IQ’s. Ment. Retard. 14: 30–31 (1976).PubMedGoogle Scholar
  11. Cox, D. A genetic study of Arileon’s disease. Evidence for heterogeneity. Am. J. Hum. Genet. 24: 646–666 (1972).PubMedGoogle Scholar
  12. Crocker, A. Families under stress. The diagnosis of Hurler’s syndrome. Postgrad. Med. 51: 223–229 (1972).PubMedGoogle Scholar
  13. Cusworth, D., and Dent, C. Homocystinuria. Br. Med. Bull. 23 (1): 42–47 (1969).Google Scholar
  14. Dacremont, G. Niemann-Pick disease. N. Engl. J. Med. 289: 592–593 (1973).PubMedGoogle Scholar
  15. Dalton, J., and Epstein, H. Counseling parents of mildly retarded children. Soc. Casework 44: 523–530 (1963).Google Scholar
  16. Denhoff, E. Cerebral Palsy: The preschool years. Thomas, Springfield, Ill. (1967).Google Scholar
  17. Donnelly, P., and DiFerrante, N. Reliability of the Booth-Nadler technique for the detection of Hunter heterozygotes. Pediatrics 56: 429–433 (1975).PubMedGoogle Scholar
  18. Dubois, E., and Kaplan, B. Letters. S-L-E and Klinefelter’s syndrome. Lancet 1 (7950): 93 (1976).PubMedCrossRefGoogle Scholar
  19. Dumanrs, K., Gaskill, D., and Kitzmiller, N. “Le Cri-du-Chat” (crying cat) syndrome. Am. J. Dis. Child. 108: 533 (1972).Google Scholar
  20. Eisen, J. Screening program for Tay-Sachs disease. Nebr. State Med. J. 58: 166–167 (1973).Google Scholar
  21. Elias, S., and Mahoney, T. Prenatal diagnosis of trisomy 13 with decision not to terminate pregnancy. Obstet. Gynecol. 47: 75S - 76S (1976).PubMedGoogle Scholar
  22. Ellingson, R., Menolascino, F., and Eisen, J. Clinical-EEG relationships in mongoloids confirmed by karyotype. Am. J. Ment. Def. 74 (5): 645–650 (1970).Google Scholar
  23. Elsas, L. Classical maple syrup urine disease. Cofactor resistance. Metabolism 21: 929–944 (1972).PubMedCrossRefGoogle Scholar
  24. Francis, M., and Smith, R. Polymetric collagen of skin in osteogenesis imperfecta, homocystinuria, and Ehlers-Danlos and Marfan syndromes. Birth Def. 11: 15–21 (1975).Google Scholar
  25. Francone, C. My battle against Wilson’s disease. Am.J. Nurs. 76: 247–249 (1976).PubMedGoogle Scholar
  26. Frankenburg, W., Goldstein, A., and Olson, C. Behviorial consequences of increased phenylalanine intake by phenylketonuric children. A pilot study describing a methodology. Am. J Ment. Def. 77: 524–532 (1973).Google Scholar
  27. Fujimoto, W. Mental retardation and self-destructive behavior. Clinical and biochemical features of the Lesch-Nyhan syndrome, in The Genetic, Metabolic, and Developmental Aspects of Mental Retardation. R.F. Murray and P.L. Rosser, eds. Thomas, Springfield, Ill. (1972).Google Scholar
  28. Garrard, S., and Richmond, J. Diagnosis in mental retardation, in Medical Aspects of Mental Retardation, C. Carter, ed. Thomas, Springfield, Ill. (1965).Google Scholar
  29. Gordon, N. Pediatric Neurology for the Clinician. Spastics Int. Med. Pub. Lippincott, Philadelphia (1976).Google Scholar
  30. Groll, M., and Cooper, M. Menstrual function in Turner’s syndrome. Obstet. Gynecol. 47: 225–226 (1976).PubMedGoogle Scholar
  31. Grossman, H. (ed.). Manual on Terminology and Classification in Mental Retardation, rev. ed. Am. Assoc. Ment. Def., Washington, D.C. (1973).Google Scholar
  32. Hill, H. Detection of inborn errors of metabolism. Galactosemia. Science 179: 1136–1139 (1973).PubMedCrossRefGoogle Scholar
  33. Hirst, A., Jr., and Gore, I. Marfan’s syndrome. A review. Progr. Cardiovasc. Dis. 16: 187–198 (1973).CrossRefGoogle Scholar
  34. Leonard, M. Homocystinuria. A differential diagnosis of Marfan’s syndrome. Oral Surg. 35: 214–219 (1973).CrossRefGoogle Scholar
  35. Lesch, M., and Nyhan, W. A familial disorder of uric acid metabolism and functin. J. Pediatr. 36: 561 (1964).Google Scholar
  36. Levin, B., and Jacoby, N. Mucopolysaccharidosis. Proc. R. Soc. Med. 65: 339–341 (1972).PubMedGoogle Scholar
  37. Libert, J., Toussaint, D., and Guiselings, R. Ocular findings in Niemann-Pick disease. Am. J. Ophthalmol. 80: 991–1002 (1975).PubMedGoogle Scholar
  38. Machill, G., and Knopp, A. On the population genetics of phenylketonuria in the German Democratic Republic. Hum. Genet. (formerly Humangenetik, Berlin) 31: 107–111 (1976).PubMedCrossRefGoogle Scholar
  39. McKusick, V. Concise outline of medical genetics. Med. Times 94: 807–815 (1966).PubMedGoogle Scholar
  40. Menolascino, F. Psychiatric aspects of mental retardation in children under eight. Am. 1. Orthopsychiatry 35: 852–861 (1965).CrossRefGoogle Scholar
  41. Menolascino, F. Changing developmental perspectives in Down’s syndrome. Child Psychiatr. Hum. Deve. 4 (4): 85 (1974).Google Scholar
  42. Michael, E. Studies on the biochemical basis of the Marfan syndrome. A review. Ala. J. Med. Sci. 13: 54–58 (1976).PubMedGoogle Scholar
  43. Michaels, J., and Schucman, H. Observations on the psychodynamics of parents of retarded children. Am. J. Men. Def. 66: 568–573 (1962).Google Scholar
  44. Milunsky, A. Prenatal diagnosis of genetic disorders. An analysis of experience with 600 cases. DAMA 230: 232–235 (1974).Google Scholar
  45. National Institute of Health. Facts about Mongolism, for Women Over 35 (DHEW No. 74–536 ). U.S. Gov. Prtg. Off., Washington, D.C. (1974).Google Scholar
  46. National Institute of Health. What Are the Facts About Genetic Disease? (DHEW No. 75–370 ). U.S. Gov. Prtg. Off., Washington, D.C. (1975).Google Scholar
  47. O’Brien, J. Tay-Sachs disease. From enzyme to prevention. Proc. Fed. Am. Soc. Exp. Biol. 32: 191199 (1973).Google Scholar
  48. Rockson, S., Stone, R., Van der Weyden, M., and Kelley, W. Lesch-Nyhan syndrome. Evidence for abnormal adrenergic function. Science 186: 934–935 (1974).PubMedCrossRefGoogle Scholar
  49. Ross, A. The Exceptional Child in the Family. Grune & Stratton, New York (1964).Google Scholar
  50. Russell, A., Statler, M., Shina, A., and Perlman, M. Proceedings. Neonatal diagnosis of maple syrup urine disease and the influence of exchange blood transfusion. Isr. J. Med. Sci. 11: 1218–1219 (1975).Google Scholar
  51. Santavuori, P. Infantile type of so-called neuronal aroid-lipofuscinosis. A clinical study of 15 patients. J. Neurol. Sci. 18: 257–267 (1973).PubMedCrossRefGoogle Scholar
  52. Schlottman, R. Social and play behaviors of institutionalized mongoloid and nonmongoloid retarded children. J. Psychol. 91: 201–206 (1975).CrossRefGoogle Scholar
  53. Soltan, H. PKU screening. Can. Med. Assoc. J. 108: 961 (1973).PubMedGoogle Scholar
  54. Stoddard, H. The relation of parental attitudes and achievements of severely mentally retarded children. Am. J. Ment. Def. 63: 575–598 (1959).Google Scholar
  55. Taylor, A. Patau’s, Edwards’, and Cri-du-Chat syndrome. A tabulated summary of current findings. Dec. Med. Child Neurol. 9: 78–86 (1967).CrossRefGoogle Scholar
  56. Vannas, A., Hogan, M., Golbus, M., and Wood, I. Lens changes in galactosemic fetus. Am. J. Ophthalmol. 80: 726–733 (1975).PubMedGoogle Scholar
  57. Vaughn, V. Growth and development (Chap. 2), in Nelson: Textbook of Pediatrics, 10th ed. V.C. Vaughn and R.J. McKay, eds. Saunders, Philadelphia (1975).Google Scholar
  58. Walske, J. Copper chelaton in patients with Wilson’s disease. A comparison of penicillamine and triethylene tetramine dihydrochloride. J. Med. (Oxford ) 42: 441–452 (1973).Google Scholar
  59. Wendel, U. Rapid diagnosis of maple syrup urine disease (branched chain ketoaciduria) by microenzyme assay in leukodytes and fibroblasts. Clin. Chim. Acta. 45: 433–440 (1973).PubMedCrossRefGoogle Scholar
  60. Wolfensberger, W. Counseling the parents of the retarded. In Mental Retardation. A.A. Baumeister, ed. Aldine, Chicago (1967).Google Scholar

Copyright information

© Spectrum Publications 1982

Authors and Affiliations

  • Michael Egger

There are no affiliations available

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