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Infantile hypertrophic pyloric stenosis: approaches to liability

  • J. C. Bear
Part of the Advances in the Study of Birth Defects book series (ASBD, volume 6)

Abstract

Among the common birth defects of man, infantile hypertrophic pyloric stenosis (IHPS) has an exceptionally straightforward and satisfactory clinical management. The epidemiology and genetics of the condition are relatively well studied, and because onset of IHPS usually occurs days or weeks after birth, several aspects of perinatal life have been investigated as possibly relevant in IHPS liability. The pathogenesis of IHPS, however, remains unknown and relatively little studied.

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References

  1. 1.
    Cockayne, E. A. and Penrose, L. S. (1943). The genetics of congenital pyloric stenosis. Ohio J. Sci., 43, 1Google Scholar
  2. 2.
    Carter, C. O. and Evans K. A. (1969). Inheritance of congenital pyloric stenosis. J. Med. Genet., 6, 233CrossRefPubMedPubMedCentralGoogle Scholar
  3. 3.
    Dodge, J. A. (1975). Infantile hypertrophic pyloric stenosis in Belfast, 1957–1969. Arch. Dis. Child., 50, 171CrossRefPubMedPubMedCentralGoogle Scholar
  4. 4.
    MacMahon, B., Record, R. G. and McKeown, T. (1951). Congenital pyloric stenosis. An investigation of 578 cases. Br. J. Soc. Med., 5, 185PubMedPubMedCentralGoogle Scholar
  5. 5.
    McKeown, T., MacMahon, B. and Record, R. G. (1951). The familial incidence of congenital pyloric stenosis. Ann. Eugen., 16, 260CrossRefPubMedGoogle Scholar
  6. 6.
    Adelstein, P. and Fedrick, J. (1976). Pyloric stenosis in the Oxford Record Linkage Study Area. J. Med. Genet., 13, 439CrossRefPubMedPubMedCentralGoogle Scholar
  7. 7.
    Shim, W. K. T., Campbell, M. A. and Wright, S. W. (1970). Pyloric stenosis in the racial groups of Hawaii. J. Pediatr., 76, 89CrossRefPubMedGoogle Scholar
  8. 8.
    Spence, M. A. and Gladstien, K. (1978). Pyloric stenosis and the simulation of Mendelism. In Morton, N. E. and Chung, C. S. (eds.) Genetic Epidemiology, pp. 331–351. (New York: Academic Press)Google Scholar
  9. 9.
    Lewis, F. L. K. (1944). Pyloric stenosis in identical twins. Br. Med. J., 1, 221CrossRefPubMedPubMedCentralGoogle Scholar
  10. 10.
    Dodge, J. A. (1973). Genetics of hypertrophic pyloric stenosis. Clin. Gastroenterol., 2, 523Google Scholar
  11. 11.
    Dodge, J. A. (1973). Infantile pyloric stenosis: inheritance, psyche and soma. Ir. J. Med. Sci., 142, 6CrossRefPubMedGoogle Scholar
  12. 12.
    Dodge, J. A. (1975). The stomach. In Anderson, C. M. and Burke, V. (eds.) Paediatric Gastroenterology, pp. 81–123. (Oxford: Blackwell Scientific)Google Scholar
  13. 13.
    Freund, H., Berlatzky, Y., Katzenelson, R. and Schiller, M. (1976). Diagnosis of pyloric stenosis. Lancet, 1, 473CrossRefGoogle Scholar
  14. 14.
    Benson, C. D. and Lloyd, J. R. (1964). Infantile pyloric stenosis. Am. J. Surg., 107, 429CrossRefPubMedGoogle Scholar
  15. 15.
    Schärli, A., Sieber, W. K. and Kiesewetter, W. B. (1969). Hypertrophic pyloric stenosis at the Children’s Hospital of Pittsburgh from 1912 to 1967. J. Pediatr. Surg., 4, 108CrossRefPubMedGoogle Scholar
  16. 16.
    Dodge, J. A. (1972). Infantile pyloric stenosis: a multifactorial condition. Birth Defects: Orig. Art. Ser., 8, 15 (New York: National Foundation)Google Scholar
  17. 17.
    Prosser, R. (1965). Infantile hypertrophic pyloric stenosis. Pediatr. Surg., 58, 881Google Scholar
  18. 18.
    Czeizel A. (1972). Birthweight distribution in congenital pyloric stenosis. Arch. Dis. Child., 47, 978CrossRefPubMedPubMedCentralGoogle Scholar
  19. 19.
    Berglund, G. and Rabo, E. (1973). A long-term follow-up investigation of patients with hypertrophic pyloric stenosis — with special reference to heredity and later morbidity. Acta Paediatr. Scand., 62, 130CrossRefPubMedGoogle Scholar
  20. 20.
    Wanscher, B. and Jensen, H.-E. (1971). Late follow-up studies after operation for congenital pyloric stenosis. Scand. J. Gastroenterol., 6, 597CrossRefPubMedGoogle Scholar
  21. 21.
    Dye, T. E., Vidais, V. G., Lockhart, C. E. and Snider, W. R. (1979). Adult hypertrophic pyloric stenosis. Am. Surgeon, 45, 478PubMedGoogle Scholar
  22. 22.
    Walton, T. P. (1978). Pyloric stenosis. Am. Surgeon, 44, 329PubMedGoogle Scholar
  23. 23.
    Fenwick, T. (1953). Familial hypertrophic pyloric stenosis. Br. Med. J., 2, 12CrossRefPubMedPubMedCentralGoogle Scholar
  24. 24.
    Woo-Ming, M. (1961). Familial relationship between adult and infantile hypertrophic pyloric stenosis. Br. Med. J., 1, 476CrossRefPubMedPubMedCentralGoogle Scholar
  25. 25.
    Zavala, C., Bolio, A., Montalvo, R. and Lisker, R. (1969). Hypertrophic pyloric stenosis: adult and congenital types occurring in the same family. J. Med. Genet., 6, 126CrossRefPubMedPubMedCentralGoogle Scholar
  26. 26.
    Leek, I. (1976). Descriptive epidemiology of common malformations (excluding central nervous system defects). Br. Med. Bull., 32, 45CrossRefGoogle Scholar
  27. 27.
    Ford, N., Brown, A. and McCreary, J. F. (1941). Evidence of monozygosity and disturbance of growth in twins with pyloric stenosis. Am. J. Dis. Child., 61, 41Google Scholar
  28. 28.
    Carter, C. O. (1961). The inheritance of congenital pyloric stenosis. Br. Med. Bull., 17, 251CrossRefPubMedGoogle Scholar
  29. 29.
    Dodge, J. A. (1971). Abnormal distribution of ABO blood groups in infantile pyloric stenosis. J. Med. Genet., 8, 468CrossRefPubMedPubMedCentralGoogle Scholar
  30. 30.
    Dodge, J. A. (1974). Maternal factor in infantile hypertrophic pyloric stenosis. Arch. Dis. Child., 49, 825CrossRefPubMedPubMedCentralGoogle Scholar
  31. 31.
    Edwards, J. H. (1965). The meaning of the associations between blood groups and disease. Ann. Hum. Genet., 29, 77CrossRefGoogle Scholar
  32. 32.
    Walgren, A. (1960). Is the rate of hypertrophic pyloric stenosis declining? Acta Paediatr., 49, 530CrossRefGoogle Scholar
  33. 33.
    McLean, M. M. (1956). The incidence of infantile pyloric stenosis in the north-east of Scotland. Arch. Dis. Child., 31, 481CrossRefPubMedPubMedCentralGoogle Scholar
  34. 34.
    Campbell, M. A. (1969). The question of seasonal variation of pyloric stenosis. J. Pediatr., 74, 1006CrossRefPubMedGoogle Scholar
  35. 35.
    Herweg, J. C., Middlekamp, J. N., Thornton, H. K. and Reed, C. A. (1962). A search into the etiology of hypertrophic pyloric stenosis. J. Pediatr., 61, 309CrossRefPubMedGoogle Scholar
  36. 36.
    McKeown, T., MacMahon, B. and Record, R. G. (1951). The incidence of congenital pyloric stenosis related to birth rank and maternal age. Ann. Eugen., 16, 249CrossRefPubMedGoogle Scholar
  37. 37.
    Gladstien, K. and Spence, M. A. (1978). A statistical analysis of birth-order effects with application to data on pyloric stenosis. Ann. Hum. Genet., 42, 213CrossRefPubMedGoogle Scholar
  38. 38.
    Barker, D. J. P. and Record, R. G., (1967). The relationship of the presence of disease to birth order and maternal age. Am. J. Hum. Genet., 19, 433PubMedPubMedCentralGoogle Scholar
  39. 39.
    Still, G. F., (1927). Place-in-family as a factor in disease. Lancet, 2, 795Google Scholar
  40. 40.
    Carter, C. O. (1965). The inheritance of common congenital malformations. In Steinberg, A. G. and Beam, A. G. (eds.) Progress in Medical Genetics. Vol. IV, pp. 59–84. (New York: Grune & Stratton)Google Scholar
  41. 41.
    Osawa, M., Yamamoto, Y., Mitsuya, Y., Tsukamoto, A., Fukuyama, Y. and Tanaka, K. (1976). A clinical genetic study on congenital hypertrophic pyloric stenosis. Jpn. J. Hum. Genet., 20, 35Google Scholar
  42. 42.
    Henderson, J. L., Brown, J. J. M. and Taylor, W. C. (1952). Clinical observations on pyloric stenosis in premature infants. Arch. Dis. Child., 27, 173CrossRefPubMedPubMedCentralGoogle Scholar
  43. 43.
    Wilson, M. G. (1960). Pyloric stenosis in premature infants. J. Pediatr., 56, 490CrossRefPubMedGoogle Scholar
  44. 44.
    Dodge, J. A. (1972). Psychosomatic aspects of infantile pyloric stenosis. J. Psychosom. Res., 16, 1CrossRefPubMedGoogle Scholar
  45. 45.
    Revill, S. I. and Dodge, J. A. (1978). Psychological determinants of infantile pyloric stenosis. Arch. Dis. Child., 53, 66CrossRefPubMedPubMedCentralGoogle Scholar
  46. 46.
    McKeown, T., MacMahon, B. and Record, R. G. (1952). Evidence of post-natal environment influence in the aetiology of infantile pyloric stenosis. Arch. Dis. Child., 27, 386CrossRefPubMedPubMedCentralGoogle Scholar
  47. 47.
    Gerrard, J. W., Waterhouse, J. A. H. and Maurice, D. G. (1955). Infantile pyloric stenosis. Arch. Dis. Child., 30, 493CrossRefPubMedPubMedCentralGoogle Scholar
  48. 48.
    Thompson, W. A. and Gaisford, W. F. (1935). Congenital pyloric stenosis (with observations based on 209 consecutive cases). Br. Med. J., 2, 1037CrossRefPubMedPubMedCentralGoogle Scholar
  49. 49.
    Carter, C. O. and Powell, B. W. (1954). Two-generation pyloric stenosis. Lancet, 1, 746CrossRefGoogle Scholar
  50. 50.
    McKeown, T. and MacMahon, B. (1955). Infantile hypertrophic pyloric stenosis in parent and child. Arch. Dis. Child., 30, 497CrossRefPubMedPubMedCentralGoogle Scholar
  51. 51.
    Carter, C. O. (1969). Genetics of common disorders. Br. Med. Bull., 25, 52CrossRefPubMedGoogle Scholar
  52. 52.
    Falconer, D. S. (1965). The inheritance of liability to certain diseases, estimated from the incidence among relatives. Ann. Hum. Genet., 29, 51CrossRefGoogle Scholar
  53. 53.
    Carter, C. O. (1972). Genetics of infantile pyloric stenosis. Birth Defects: Orig. Art. Ser., 8, 12 (New York: National Foundation)Google Scholar
  54. 54.
    Carter, C. O. (1963). The genetics of common malformations. In Second International Conference on Congenital Malformations, pp. 306–313. (New York: The International Medical Congress Ltd)Google Scholar
  55. 55.
    Carter, C. O. (1970). Multifactorial inheritance revisited. In Fraser, F. C. McKusick, V. A. and Robinson, R. (eds.) Congenital Malformations, pp. 227–232. (Amsterdam: Excerpta Medica)Google Scholar
  56. 56.
    Carter, C. O. (1976). Genetics of common single malformations. Br. Med. Bull., 32, 21CrossRefPubMedGoogle Scholar
  57. 57.
    Kidd, K. K. and Spence, M. A. (1976). Genetic analyses of pyloric stenosis suggesting a specific maternal effect. J. Med. Genet., 13, 290CrossRefPubMedPubMedCentralGoogle Scholar
  58. 58.
    Reich, T., James, J. W. and Morris, C. A. (1972). The use of multiple thresholds in determining the mode of transmission of semi-continuous traits. Ann. Hum. Genet., 36, 163CrossRefPubMedGoogle Scholar
  59. 59.
    Kidd, K. K., Reich, T. and Kessler, S. (1973). A genetic analysis of stuttering suggesting a single major locus. Genetics, 74, S137Google Scholar
  60. 60.
    Gladstien, K., Lange, K. and Spence, M. A. (1978). A goodness-of-fit test for the polygenic threshold model: application to pyloric stenosis. Am. J. Med. Genet., 2, 7CrossRefPubMedGoogle Scholar
  61. 61.
    Morton, N. E. and MacLean, C. J. (1974). Analysis of family resemblance. III. Complex segregation of quantitative traits. Am. J. Hum. Genet., 26, 489PubMedPubMedCentralGoogle Scholar
  62. 62.
    Lalouel, J. M., Morton, N. E., MacLean, C. J. and Jackson, J. (1977). Recurrence risks in complex inheritance with special regard to pyloric stenosis. J. Med. Genet., 14, 408CrossRefPubMedPubMedCentralGoogle Scholar
  63. 63.
    Knox, G. (1958). On the nature of the determinants of congenital pyloric stenosis. Br. J. Prev. Soc. Med., 12, 188PubMedPubMedCentralGoogle Scholar
  64. 64.
    Knox, G. (1963). The family characteristics of children with clefts of lip and palate. Acta Genet., Basel, 13, 299PubMedGoogle Scholar
  65. 65.
    Niswander, J. D., Chung, C. S., MacLean, C. J. and Dronamaraju, K. (1972). Sex ratio and cleft lip with or without cleft palate. Lancet, 2, 858CrossRefPubMedGoogle Scholar
  66. 66.
    Bear, J. C. (1973). The association of fetal wastage with facial cleft conditions. Cleft Palate J., 10, 346PubMedGoogle Scholar
  67. 67.
    Bear, J. C. (1978). Spontaneous abortion, sex ratio and facial cleft malformations. Clin. Genet., 13, 1CrossRefPubMedGoogle Scholar
  68. 68.
    Bear, J. C. (1978). The association of sex ratio anomalies with pyloric stenosis. Teratology, 17, 19CrossRefPubMedGoogle Scholar
  69. 69.
    Armitage, G. and Rhind, J. A. (1951). The fate of the tumour in infantile hypertrophic pyloric stenosis. Br. J. Surg., 39, 39CrossRefPubMedGoogle Scholar
  70. 70.
    Dickinson, S. J. and Brant, E. E. (1967). Congenital pyloric stenosis: roentgen findings 52 years after gastroenterostomy. Surgery, 62, 1092PubMedGoogle Scholar
  71. 71.
    Friesen, S. R., Boley, J. O. and Miller, D. R. (1956). The myenteric plexus of the pylorus: its early normal development and its changes in hypertrophic pyloric stenosis. Surgery, 39, 21PubMedPubMedCentralGoogle Scholar
  72. 72.
    Friesen, S. R. and Pearse, A. G. E. (1963). Pathogenesis of congenital pyloric stenosis: histochemical analyses of pyloric ganglion cells. Surgery, 53, 604PubMedGoogle Scholar
  73. 73.
    Jona, J. Z. (1978). Electron microscopic observations in infantile hypertrophic pyloric stenosis (IHPS). J. Pediatr. Surg., 13, 17CrossRefPubMedGoogle Scholar
  74. 74.
    Bruckner, W. L., Snow, H. D. and Fonkalsrud, E. W. (1970). Gastric secretion in the canine fetus following maternal stimulation: experimental studies on placental transfer of insulin, histamine, and gastrin. Surgery, 67, 360PubMedGoogle Scholar
  75. 75.
    Dodge, J. A. (1970). Production of duodenal ulcers and hypertrophic pyloric stenosis by administration of pentagastrin to pregnant and newborn dogs. Nature (Lond.), 225, 284CrossRefGoogle Scholar
  76. 76.
    Karim, A. A., Morrison, J. E. and Parks, T. G. (1974). The role of pentagastrin in the production of canine hypertrophic pyloric stenosis and pyloroduodenal ulceration. Br. J. Surg., 61, 327PubMedGoogle Scholar
  77. 77.
    Dodge, J. A. and Karim, A. A. (1976). Induction of pyloric hypertrophy by pentagastrin. Gut, 17, 280CrossRefPubMedPubMedCentralGoogle Scholar
  78. 78.
    Spitz, L. and Zail, S. S. (1976). Serum gastrin levels in congenital hypertrophic pyloric stenosis. J. Pediatr. Surg., 11, 33CrossRefPubMedGoogle Scholar
  79. 79.
    Bleicher, M. A., Shandling, B., Zingg, W., Karl, W. A. and Track, N. S. (1978). Increased serum immunoreactive gastrin levels in idiopathic hypertrophic pyloric stenosis. Gut, 19, 794CrossRefPubMedPubMedCentralGoogle Scholar
  80. 80.
    Werlin, S. L., Grand, R. J. and Drum, D. E. (1978). Congenital hypertrophic pyloric stenosis: the role of gastrin reevaluated. Pediatrics, 61, 883PubMedGoogle Scholar
  81. 81.
    Moazim, F., Rodgers, B. M., Talbert, J. L. and McGuigan, J. E. (1978). Fasting and postprandial serum gastrin levels in infants with congenital hypertrophic pyloric stenosis. Ann. Surg., 188, 623CrossRefGoogle Scholar
  82. 82.
    Hambourg, M. A., Mignon, M., Ricour, C., Accary, J. and Pellerin, D. (1979). Serum gastrin levels in hypertrophic pyloric stenosis of infancy. Arch. Dis. Child., 54, 208CrossRefPubMedPubMedCentralGoogle Scholar
  83. 83.
    Janik, J. A., Akbar, A. M., Burrington, J. D. and Burke, G. (1978). The role of gastrin in congenital hypertrophic pyloric stenosis. J. Pediatr. Surg., 13, 151CrossRefPubMedGoogle Scholar
  84. 84.
    Rogers, I. M., Drainer, I. K., Moore, M. R. and Buchanan, K. D. (1975). Plasma gastrin in congenital hypertrophic pyloric stenosis. A hypothesis disproved? Arch. Dis. Child., 50, 467CrossRefPubMedPubMedCentralGoogle Scholar
  85. 85.
    Rogers, I. M., Drainer, I. K., Dougal, A. J., Black, J. and Logan, R. (1979). Serum cholecystokinin, basal acid secretion, and infantile pyloric stenosis. Arch. Dis. Child., 54, 773CrossRefPubMedPubMedCentralGoogle Scholar

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  • J. C. Bear

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