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Genetic RNA-RNA Recombination in Positive-Stranded RNA Viruses of Plants

  • Jozef J. Bujarski
  • Peter D. Nagy
Chapter

Abstract

Plus-stranded (+) RNA viruses replicate without generating DNA intermediates. Nevertheless, like DNA-based organisms, they undergo evolution and adaptation to a new environment. The mechanisms involved in generating the diversity among (+) RNA viruses include such processes as high-frequency point mutagenesis, homologous and nonhomologous recombination between related RNA viruses, reassortment among multipartite RNA genomes, or crossings with cellular RNAs (King 1988; Strauss & Strauss 1988; Goldbach 1990; Lai 1992; Dolja & Carrington 1992). The nucleotide sequences of more than 100 viral (+) RNA genomes are available. This, surprisingly, revealed the modular nature of the assembly of their genome, among such sequence moduls as core RNA replicase genes, accessory genes, movement and capsid genes as well as cis-acting elements (Gibbs 1987; Zimmern 1988; Goldbach et al. 1991; Dolja & Carrington 1992). This supported the role of genetic recombination in virus evolution and maintenance. Both nonhomologous and homologous recombination events have been described for a limited number of animal and plant RNA viruses. In this chapter we review recombination studies in (+) RNA viruses with the emphasis put on plant RNA viruses.

Keywords

Tomato Spotted Wilt Virus Tobacco Rattle Virus Alfalfa Mosaic Virus Brome Mosaic Virus Satellite RNAs 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Abbreviations

BMV

brome mosaic virus

TCV

turnip crinkle virus

DI RNA

defective-interfering RNA

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© Springer Science+Business Media Dordrecht 1994

Authors and Affiliations

  • Jozef J. Bujarski
  • Peter D. Nagy

There are no affiliations available

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