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Modification of antibody responses during non-specific acute inflammation (Abstract)

  • I. Florentin
  • M. Pelletier
  • G. Mathe
  • J. P. Giroud
Part of the Inflammation: Mechanisms and Treatment book series (FTIN, volume 4)

Abstract

It has been previously shown that non-specific acute inflammatory reactions are able to modify the activity of lymphocytes and macrophages. In the present work we investigated whether such a reaction could interfere with the development of antibody responses. For this purpose, (C57B1/6xDBA/2)F1 mice were immunized with sheep red blood cells (SRBC) as a thymus dependent antigen or with TNP-LPS as a thymus-independent one, from 1 h to 5 days after the intrapleural injection of calcium pyrophosphate (CaPP) microcrystals or a dextran solution (MW 40 000).

Keywords

Fold Increase Inflammatory Process Antibody Response Inflammatory Stimulus Press Limited 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© MTP Press Limited 1980

Authors and Affiliations

  • I. Florentin
    • 1
  • M. Pelletier
    • 1
  • G. Mathe
    • 1
  • J. P. Giroud
    • 1
  1. 1.France

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